Unusually large quiescent ancient schwannoma of hypoglossal nerve

Abstract

Ancient schwannoma is considered as a variant of schwannoma, comprising about 10% of all schwanommas. Schwannoma is a benign neoplasm derived from the nerve sheath of peripheral motor, sensory and sympathetic nerves and from the cranial nerve pairs. It usually presents as a solitary soft-tissue lesion which is slow growing, encapsulated and is often associated with nerve attached peripherally. Diagnosis is often confirmed with the microscopic examination. The long standing schwannoma attributes to degenerative changes and is termed "ancient" schwannoma. Present case is of a 68-year-old female patient who reported with an asymptomatic large swelling below mandible on the left side since last 23 years. The lesion was surgically excised under general anesthesia.

Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case

“…Independently from the nerve that is affected, surgical treatment consists of systematic exeresis of the lesions. This has been furthermore confirmed by the experience of the present authors and by case reports (2,(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)30,31). In fact, all except one of the cases were treated surgically.…”

“…In almost all cases, there are varying degrees of paresis of the HyN, which appear as ipsilateral deviation, hemiatrophy and fasciculations of the tongue. These symptoms may be accompanied by hoarseness, intermittent-to-persistent headaches, dysarthria, slurred speech, swallowing difficulties and throat cramps (2,4,(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28). Whereas the effects on the specific functions of the nerve may be attributable to the local damage of the tumour on the nerve, these types of lesions, particularly when they increase in volume, may determine mass effects on surrounding or adjacent structures; for example, Mariniello et al (19) reported on the case of a patient who exhibited signs of cerebellar ataxia, right-sided hypotonia and increased intracranial pressure.…”

Intraosseous Schwannoma of the Left Infra Temporal Region Involving Oral Cavity: A Case Report

“…The possibility of an intraosseous schwannoma was not considered at first because of the extreme rarity of this location. Differential diagnosis of fibroma, fibrolipoma, neurofibroma, schwannoma, fibromyxoma or leiomyoma was considered 8 . The histopathological examination provided a definitive diagnosis for this case.…”

Giant paratracheal ancient schwannoma in 57-year-old male patient: case report

“…These nerves do not have a Schwann cell sheath [3][4][5]. Locating the nerve of origin is difficult and only 50 % of all cases can be correlated with the nerve of origin [6].…”