Unusual Rearrangements in Cyclohex-3-ene-1-carboxamide Derivatives: Pathway to Bicyclic Lactones
Ozlem Gundogdu,
Sertan Aytaç,
Ertan Şahin
et al.
Abstract:The synthesis of new bicyclic lactone derivatives was
carried out
starting from 2-methyl/phenyl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione. 6-(Hydroxymethyl)-N-methyl/phenylcyclohex-3-ene-1-carboxamide
derivatives were obtained from the reduction of tetrahydro-1H-isoindole-1,3(2H)-diones with NaBH4. Bromination and epoxidation reactions of both compounds
were examined, and the structures of the resulting products were determined
by spectroscopic methods. Substituted bicyclic lactone compounds,
which are i… Show more
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