Unusual primary secreting germ cell tumor of the spine

Abstract

<jats:p>✓ The authors describe a young man with a rare primary spinal germ cell tumor that secreted β–human chorionic gonadotropin. The tumor was resected, and six courses of adjuvant chemotherapy consisting of cisplatin, bleomycin and etoposide were administered together with irradiation to the craniospinal area. An additional dose of radiation was delivered to the tumor site after the first four chemotherapy sessions. The patient was well without any neurological deficit or iatrogenic sequela 33 months after diagnosis. The occurrence of this rare tumor located primarily in the spine warrants attention in pathological studies of spinal tumors in young patients.</jats:p>

Metastatic choriocarcinoma to the lumbar spine: Case report and review of literature

“…[ 5 17 ] Of note, there are several cases reported with spinal metastases containing mixed germ cell tumors with choriocarcinoma elements; these mixed tumors, however, do not necessarily bear a worse prognosis on account of the choriocarcinoma mixture. [ 12 17 19 ]…”

MR Imaging of Primary Spinal Germinoma: A Case Report and Review of the Literature

“…There were 13 male and 10 female patients with ages ranging from 5 to 43 years (mean age: 25 years). The tumors predisposed to arise from the lower thoracic and lumbar spinal region 1–23 . Only one case occurred in the middle portion of cervical spinal cord 15 .…”

A Case of Lumbar Metastasis of Choriocarcinoma Masquerading as an Extraosseous Extension of Vertebral Hemangioma

“…The lung and brain have been described as the most common sites for metastasis in the literature 1,2,4,11,12,15,20,21,23,25) . Yet, metastasis in the musculoskeletal system, such as the spine, is extremely rare and this can be seen from the scant reported cases 4,[14][15][16]20,21) . This current report presents an unusual metastatic choriocarcinoma in the lumbar spine and it extended to the epidural space.…”