Unusual Presentation of Neonatal Behcets Disease

Jog, S M; Patole, Sanjay; Koh, Guan; Whitehall, John

doi:10.1055/s-2001-16994

Cited by 25 publications

(15 citation statements)

References 13 publications

(15 reference statements)

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“…One case of intrauterine growth restriction was reported in the literature (31) but was never reported in the large series. Similarly, neonatal BD was reported only in case reports (15)(16)(17)(18)27).…”

Section: Resultsmentioning

confidence: 99%

Behçet's Disease and Pregnancy

Noël

Wechsler

Nizard

et al. 2013

Arthritis & Rheumatism

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Objective. To describe the interplay between Behçet's disease (BD) and pregnancy.Methods. This retrospective study included 76 pregnancies in 46 patients fulfilling the international criteria for BD. The median age of the patients at the time of entry into the study was 28.4 years (interquartile range 22.8-30.9 years). Patients were used as their own historical controls to assess the incidence of BD flares during pregnancy and before or after pregnancy. Factors associated with the occurrence of complications during pregnancy were assessed.Results. Among the 76 pregnancies with BD analyzed, 27 (35.5%) were associated with worsening of the symptoms of BD flare; oral and genital ulcerations (78.4% and 67.6%, respectively) as well as ocular complications (32.4%) were the most frequent. The mean ؎ SD annual rates of BD flares were 0.49 ؎ 0.72 during pregnancy and 1.46 ؎ 2.42 during the nonobstetric period (P ‫؍‬ 0.018). The proportion of BD flares tended to be lower in patients treated with colchicine (27.9% versus 45.4% of patients not treated with colchicine; P ‫؍‬ 0.11). The overall rate of complications during pregnancy was 15.8%. The complications included miscarriage (5 patients), cesarean delivery (3 patients), medical termination of pregnancy (2 patients), hemolysis, elevated liver enzymes, and low platelets syndrome (1 patient), and immune thrombocytopenia (1 patient). There was a statistically significant association between a history of deep vein thrombosis in BD and the risk of obstetric complications (odds ratio 7.25, 95% confidence interval 1.21-43.46, P ‫؍‬ 0.029). Neither gestational age at delivery nor neonatal outcome was influenced by BD.Conclusion. The disease course in BD seems to improve during pregnancy, mostly in patients who are treated with colchicine. Pregnancy in patients with BD appears not to be associated with an increased rate of pregnancy-related complications.

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Section: Resultsmentioning

confidence: 99%

Behçet's Disease and Pregnancy

Noël

Wechsler

Nizard

et al. 2013

Arthritis & Rheumatism

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“…The symptoms subsided within 3-9 weeks. Neurological manifestations were reported in a 34-week neonate of a diseased mother and were suspected to be ABD-related; death occurred on the 9th day [63]. A transient incident in a neonatal girl with ABD of a diseased mother has also been described [64].…”

Section: Neonatal Abdmentioning

confidence: 99%

Juvenile Adamantiades-Behçet Disease

Vaiopoulos

Kanakis²,

Kapsimali

et al. 2016

Dermatology

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Adamantiades-Behçet disease (ABD) is a chronic, multisystemic, recurrent, inflammatory vascular disorder of unknown etiology. Patients with symptoms initially appearing at the age of 16 or less are considered as cases of juvenile-onset ABD (JABD). JABD is relatively rare compared to ABD of adults, and only case reports and case studies have been published regarding this subtype of the disease. Epidemiology, clinical features, diagnosis and treatment of JABD are discussed in this review.

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“…The mean age of disease onset is 25–30 years old,1 and initial presentation in children is uncommon. Details of the presentation and clinical characteristics of juvenile-onset Behçet’s disease have been limited to case reports or small case series 2 3 4 5 6 7 8…”

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confidence: 99%

Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people

Miyazaki

Stanford

Iwata

et al. 2009

British Journal of Ophthalmology

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Purpose: There is little information on the demographic and clinical characteristics of Behcet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres.Methods: Descriptive questionnaires were collected from 25 eye centers in 14 countries. The questionnaire surveyed details of juvenile-onset Behcet's disease with uveitis. Ethnic groups, clinical features, treatments, and prognosis of pediatric-age Behcet's disease were examined on a world scale.

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Unusual Presentation of Neonatal Behcets Disease

Cited by 25 publications

References 13 publications

Behçet's Disease and Pregnancy

Behçet's Disease and Pregnancy

Juvenile Adamantiades-Behçet Disease

Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people

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