Unusual presentation of a pancreatic insulinoma in helical CT and dynamic contrast-enhanced MR imaging: case report

Iglesias, Alfonso; Arias, Mercedes; Casal, M.; Páramo, C.; Fiaño, Concepción; Brasa, J.

doi:10.1007/s003300000690

Cited by 9 publications

(2 citation statements)

References 17 publications

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“…Islet cell tumors are of neuroendocrine origin. In our experience, helical CT and contrast-enhanced MRI are complementary methods for the detection of islet cell tumors [32]; however, large comparative studies that include the latest multi-detector CT technique are needed to resolve this issue. Insulinomas and gastrinomas are the most common types of neuroendocrine tumors.…”

Section: Other Tumorsmentioning

confidence: 99%

Evaluation of focal pancreatic masses: comparison of mangafodipir-enhanced MR imaging and contrast-enhanced helical CT

Schima

Függer

2002

Eur Radiol

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The detection and characterization of pancreatic tumors as well as the reliable staging of pancreatic cancer are important tasks for radiologic evaluation. Contrastenhanced helical CT has been the standard modality for pancreatic imaging in many institutions, but MR imaging has gained a considerable role in the evaluation of patients with equivocal CT findings. Recently, the first organ-specific MR contrast agent targeted to the liver and pancreas, mangafodipir trisodium, has been registered in the European Union (EU) for use in MR imaging of the pancreas. This paper reviews technical considerations and characteristic imaging findings of man-gafodipir-enhanced MR imaging in the assessment of focal pancreatic lesions. Contrast-enhanced MRI has proven to be very helpful in the detection of small tumors or the identification of tumor-simulating lesions in patients with equivocal CT findings. Mangafodopir may improve the staging of pancreatic cancer by increasing the sensitivity of MRI in the detection of liver metastases. This review summarizes the potential of contrast-enhanced MRI and the limitations compared with contrastenhanced helical CT.Evaluation of focal pancreatic masses: comparison of mangafodipir-enhanced MR imaging and contrast-enhanced helical CT gafodipir-enhanced MR imaging of the pancreas compared with contrast-enhanced helical CT. Diagnostic evaluation of focal pancreatic massesAt our institution, patients with a clinically or sonographically suspected pancreatic mass are referred for a contrast-enhanced CT or MRI study, depending on clinical suspicion and ultrasound findings. If a potentially re-

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Section: Other Tumorsmentioning

confidence: 99%

Evaluation of focal pancreatic masses: comparison of mangafodipir-enhanced MR imaging and contrast-enhanced helical CT

Schima

Függer

2002

Eur Radiol

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show abstract

“…Conventional contrast-enhanced CT scan and dynamic MRI scans detect insulinomas because of the tendency of insulinomas to present intense and early contrast enhancement with a washout phenomenon. [ 4 ] However, in cases of insulinomas that are not hypervascular, CT and conventional MRI may fail to detect such lesions. This false-negative result may be related to the fact that these lesions are small and masked by the contrasting blush of adjacent structures or isovascular to the pancreas.…”

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confidence: 99%