Unusual Location of Rheumatoid Nodule Case Report

AlAbdulrahman, Lamya Walid

doi:10.19080/oroaj.2020.16.555939

Cited by 2 publications

(3 citation statements)

References 10 publications

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“…Patients with intra-articular RNs are usually symptomatic with joint pain and restricted mobility, similar to this case, and excisions were done in most of these cases. One of seven cases of intra-articular RNs in the knee joint and one of two cases in the sacrococcygeal joint showed recurrence, and no recurrences were reported in the ankle and wrist joints [5][6][7][8]. On regular follow-up after six months, the patient's symptoms improved with the restoration of joint mobility and reduction in joint pain with no signs of infection or recurrence.…”

Section: Discussionmentioning

confidence: 78%

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An Unusual and Rare Location of Intra-articular Rheumatoid Nodule in the Elbow Joint - A Case Report

Porko¹,

Chowdhuri²,

Barsagade³

et al. 2023

Cureus

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Rheumatoid nodules are the most common extra-articular manifestation of rheumatoid arthritis. Intraarticular rheumatoid nodules are very rare and usually associated with clinical symptoms. Case reports of intra-articular rheumatoid nodules in the knee joint, wrist joint, ankle joint, and sacrococcygeal joint are reported. However, an intra-articular rheumatoid nodule in the elbow joint has not been reported in the literature. Herein, we report a unique and rare case of a symptomatic intra-articular rheumatoid nodule in the elbow joint of a 49-year-old female with a 15-year history of rheumatoid arthritis. The symptoms resolved after surgical excision of the nodule.

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Section: Discussionmentioning

confidence: 78%

“…However, intra-articular rheumatoid nodules are exceptionally rare. Rare cases of intra-articular rheumatoid nodules in the knee joint, wrist joint, ankle joint, and sacrococcygeal joint are reported [5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%

An Unusual and Rare Location of Intra-articular Rheumatoid Nodule in the Elbow Joint - A Case Report

Porko¹,

Chowdhuri²,

Barsagade³

et al. 2023

Cureus

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“…These cardinal features collectively define the complex landscape of RA. Moreover, RA's impact is not confined solely to joint involvement, encompassing diverse systemic manifestations such as dermatological symptoms, fever, muscle wasting, and weakness [2][3][4][5]. Rheumatoid arthritis exhibits a higher prevalence among women, particularly in their 40s [6].…”

Section: Introductionmentioning

confidence: 99%

Pan-Immune-Inflammation Index as a Biomarker for Rheumatoid Arthritis Progression and Diagnosis

Tutan,

Doğan

2023

Cureus

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Introduction Rheumatoid arthritis (RA) is a chronic autoimmune condition that causes systemic inflammation and affects multiple joints. It is characterized by joint warmth, swelling, pain, and the formation of invasive synovial tissue known as pannus, which contributes to cartilage and bone degradation. Pan-immune-inflammation value (PIV), a marker derived from complete blood count parameters, has shown promise in predicting prognosis in various cancer types and pediatric conditions associated with immune abnormalities. This study aims to explore the relationship between RA, characterized by chronic inflammation and immune system involvement, and PIV, potentially shedding light on novel insights into RA's clinical implications. Methods One hundred four participants, including 64 RA patients (both newly diagnosed and established cases) and 40 healthy controls, were included in the study. Exclusion criteria for RA patients included acute infection, cancer, diabetes, or chronic illness, while control participants were excluded for inflammatory disorders, active infection, diabetes, or malignancy. We assessed disease severity using Disease Activity Score 28 (DAS 28) and obtained complete blood count values, including neutrophil, lymphocyte, platelet, monocyte, and red cell distribution width. C-reactive peptide (CRP) and erythrocyte sedimentation rate were also added. Statistical analyses included correlation assessments, t-tests, Mann-Whitney U tests, and multivariate linear regression. A multiclass receiver operating characteristic analysis determined optimal PIV cut-off values for distinguishing control, remission, and active RA groups, with sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and odds ratios calculated. Results This study comprised a cohort of 104 participants, with a median age of 43.5±17.5. The Remission group was significantly younger than the Control group (p=0.006) but not compared to the Active RA group (p=0.393). CRP levels were significantly higher in the Active RA group (p<0.001). Neutrophil counts were highest in the Active RA group (p<0.001), as were monocyte counts. Lymphocyte counts were significantly lower in the Active RA group (p<0.001). There were no significant differences in sedimentation rate, hemoglobin, platelet count, and mean platelet volume. PIV was significantly elevated in the Active RA group (p<0.001) and higher in the Remission group than in the Control group (p=0.001). A PIV value of 353.48 exhibited 71.4% sensitivity, 86.2% specificity, 86.2% PPV, 71.4% NPV, and 78.13% test accuracy for distinguishing active rheumatoid arthritis (p<0.001). A PIV value exceeding 353.48 substantially increased the likelihood of a patient belonging to the active rheumatoid arthritis group, with a 14.62-fold higher probability. Furthermore, the study explored the relationship between clinical and laboratory variables and disease activity in RA patients, finding significant diffe...

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Unusual Location of Rheumatoid Nodule Case Report

Cited by 2 publications

References 10 publications

An Unusual and Rare Location of Intra-articular Rheumatoid Nodule in the Elbow Joint - A Case Report

An Unusual and Rare Location of Intra-articular Rheumatoid Nodule in the Elbow Joint - A Case Report

Pan-Immune-Inflammation Index as a Biomarker for Rheumatoid Arthritis Progression and Diagnosis

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