Unusual increase in reported cases of Paratyphoid A fever among travellers returning from Cambodia, January to September 2013

Abstract

From January to September 2013, a marked increase in notifications of Salmonella Paratyphi A infections among travellers returning from Cambodia occurred in France. An investigation revealed 35 cases without a common source: 21 in France, five in Germany, three in the Netherlands, one in Norway, one in the United Kingdom, four in New-Zealand. Data suggest an ongoing event that should trigger further investigation. Travellers to Cambodia should observe preventive measures including good personal hygiene and food handling practices.

Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever

“…At that time, Paratyphi A was relatively common in North America (12). Today, Paratyphi A accounts for a sizable fraction (14-64%) of all enteric fever in India, Pakistan, Nepal, Indonesia, and China (13)(14)(15)(16), but has largely disappeared from Europe and North America, except for travelers returning from South and Southeast Asia (17,18). Otherwise, little is known about its historical patterns of spread or its evolutionary history.…”

Ongoing outbreak of Salmonella enterica serovar Paratyphi A infections, Phnom Penh, Cambodia

“…Between January and September 2013, an unusual increase in the number of Salmonella Paratyphi A infections was registered in adult patients attending Sihanouk Hospital Centre of HOPE (SHCH), in Phnom Penh, Cambodia [2]. A similar trend was noted in travellers returning from Cambodia [3]. These findings were shared with the national health authorities and an epidemiological investigation was initiated; up to now, no common source or specific transmission route has been identified.…”

Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015

“…11,12 In 2013, an increase in cases of paratyphoid fever in travelers returning from Cambodia was reported, and all isolates were sensitive to fluoroquinolones. 13 Shwe and others reported that S. typhi was most commonly isolated from blood cultures among children admitted to a hospital in Yangon, 14 and all isolates were sensitive to nalidixic acid. However, there was no case of S. Paratyphi in this report.…”