Unusual Components of the Toadstool Lyophyllum connatum (Agaricales)

Abstract

thylformamide (DMF) afforded the desired glycopentapeptide allyl ester 9, whose structure was likewise confirmed by elemental analysis and spectroscopic data (I3C-NMR: 6= 102.9, C-1, Jp)c-H)= 163 Hz (dimethyl sulfoxide)).The allyl group has thus proven to be a valuable achiral carboxy-protecting group even for difficult peptide and glycopeptide syntheses, and can be used in conjunction with N-terminal Z -and Boc-protecting groups. Also noteworthy is that the four glycopeptide allyl esters 3a, 38, 6 and 9 are crystalline.

β-Hydroxyergothioneine, a New Ergothioneine Derivative from the Mushroom Lyophyllum connatum, and Its Protective Activity against Carbon Tetrachloride-Induced Injury in Primary Culture Hepatocytes

“…10) We report here the isolation and structural determination, including absolute configurations, of HERT, and the isolation and identification of three other compounds. The radical scavenging activity of these compounds is reported.…”

Screening of European Fungi for Antibacterial, Antifungal, Larvicidal, Molluscicidal, Antioxidant and Free-Radical Scavenging Activities and Subsequent Isolation of Bioactive Compounds

“…Seven fractions (A-G) were obtained. Gel filtration on Sephadex LH-20 (Pharmacia, Bromma, Sweden) with methanol-water 1 : 1 as eluent afforded 350 mg connatine (Fugmann & Steglich, 1984).…”

“…Sing. (Fugmann & Steglich, 1984). The second compound was 2(3,4dihydroxyphenyl)glycine, isolated from Cortinarius hercynicus (Pers.)…”

Chemical ecology of fungi

“…The white domecap (Lyophyllum connatum) was considered to be a good edible mushroom until it turned out that it contains mutagenic N 0 -hydroxy-N,N-dimethyl urea (13) and the amino acid connatine (14). 61 In Lactarius necator, mutagenic necatorone (15) is present. 62 In 2001, two casualties were reported aer ingestion of Tricholoma equestre, 63 a delicioustasting mushroom species.…”