Unusual complication of vaginal delivery: is misoprostal the cause?: Figure 1

Dasari, Papa; Sagili, Haritha; Udupi, G

doi:10.1136/bcr-2012-007005

Cited by 7 publications

(3 citation statements)

References 10 publications

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“…3 The known precipitating factors for CL in literature being previous interventions on the cervix 6-14% (polypectomy, LEEP, cerclage), induction of labour (threefold increased risk), use of Prostaglandins for induction of labour, precipitate labour, operative vaginal deliveries and birth weight > 3500gms. [1][2][3][4][5] However, in our experience of the known risk factors, the most common association were with induction of labour and operative vaginal delivery. In recent years the rate of induction of labour have exponentially increased.…”

Section: Discussionmentioning

confidence: 91%

Cervical lacerations: A case series

Quraishi,

Raj,

Rathore

2023

IJOGR

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Cervical laceration (CL) after vaginal delivery is one of the uncommon side effects with significant morbidity if undetected and unattended to promptly. This is however one of the common causes for postpartum haemorrhage. There are several documented risk factors for CL such as previous interventions on the cervix, induction of labour, use of Prostaglandins for induction, precipitate labour, operative vaginal deliveries and birth weight of more than 3500gm.In this article we have described a series of eleven women who were detected to have CL following vaginal delivery. One of whom had delivery of the baby through a bucket handle cervical tear with a non-dilated cervical os. Almost all of them needed multiple blood and product transfusions in view of postpartum haemorrhage with one of them developing acute kidney injury subsequently. This necessitates the need for prompt identification of CL and its needed intervention.

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Section: Discussionmentioning

confidence: 91%

Cervical lacerations: A case series

Quraishi,

Raj,

Rathore

2023

IJOGR

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“…Indeed, misoprostol increases the risk of corporal rupture in women with uterine scar 12 . Vaginal misoprostol can also decrease the macrophage function resulting in the overgrowth of clostridial organisms and developmental gangrene of gastrointestinal and reproductive tracts 13 . However, cervical lesions after prostaglandin application were more often reported in midtrimester abortions as highlighted before 5 – 7 .…”

Section: Discussionmentioning

confidence: 99%

Spontaneous delivery through a cervical tear without cervical os dilatation

Djokovic

Costa

Martins

et al. 2014

Clinical Case Reports

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Key Clinical MessageSpontaneous delivery through a cervical tear, provoked by prostaglandin-induced uterine contractions, was described in a G2P0 woman with a history of cervical dilatation and uterine curettage. This rare complication with potentially serious maternal–fetal consequences can be predicted by an aberrant cervical response to prostaglandins in parturients with previous cervical interventions.

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“…Reports in the literature indicate that worldwide, the disease has high morbidity and high mortality [1]. In its early stages, the disease may simulate common febrile conditions and other illnesses [2]. An adequate understanding of its risk factors, diagnostic features, and aetiopathogenesis is, therefore, necessary for early diagnosis, informed, aggressive treatment, and good prognosis.…”

Section: Introductionmentioning

confidence: 99%

Gas gangrene in pregnancy, parturition, and abortions requiring urological and surgical intervention: aetiopathogenesis, risk factors, and some current practices

Sapira¹,

Fiddo²

2023

Magna Sci. Adv. Res. Rev.

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Introduction: Gas gangrene in pregnancy, perinatal periods, or after an abortion has a poor prognosis. This study aims to present risk factors for the disease as reported worldwide and to discuss current concepts of its aetiopathogenesis. Materials and Methods: Using search terms, a bibliographical search was done in PubMed/ Medline and PubMed Central databases for publications on gas gangrene in pregnancy, abortions, and delivery published within the study period. Risk factors for the disease were identified by studying each of the reports. Results were presented with a discussion of the aetiopathogenesis of the disease. Results: Eighty-one (81) studies reporting on 67 patients and aetiopathogenesis of the disease were studied. The most common causes of the disease were clostridia which infected 63 (94.03%) of the patients. Identified risk factors were abortions, prolonged labor, prolonged obstructed labor, standard spontaneous vaginal delivery, Cesarean sections, episiotomy, amniocentesis, cordocentesis, ruptured uterus with fetal death, perforated appendix, pelvic tumors, trauma, foreign bodies in living tissues, accumulation of hematoma and devitalized tissues in pelvic tissues. Lethal effects of the pathogens were reported to be mediated by exotoxins produced by clostridia. Conclusion and Recommendations: Common risk factors are standard diagnostic and therapeutic procedures in pregnancy and its outcome. Local policies need to be developed for the extended use of antibiotics in normal labor and when carrying out procedures in pregnancy, delivery, and abortions. Attractive points in the aetiopathogenesis for the prevention of the disease are (i) prevention of attachment of clostridia to tissue cells and (ii) pre-pregnancy immunization of women of childbearing age.

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Unusual complication of vaginal delivery: is misoprostal the cause?: Figure 1

Cited by 7 publications

References 10 publications

Cervical lacerations: A case series

Cervical lacerations: A case series

Spontaneous delivery through a cervical tear without cervical os dilatation

Gas gangrene in pregnancy, parturition, and abortions requiring urological and surgical intervention: aetiopathogenesis, risk factors, and some current practices

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