Unusual combined cause of Takotsubo cardiomiyopathy: Hyponatremia and seizure

Şimşek, Ersin Çağrı; Emren, Sadık Volkan; Özdoğan, Öner

doi:10.14744/nci.2018.65148

Cited by 3 publications

(8 citation statements)

References 17 publications

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“…Commonly, the onset follows intense emotional or physical stress. However, a few cases of Takotsubo cardiomyopathy associated with endocrine abnormalities and electrolyte disturbances have been described, where hyponatremia-associated Takotsubo cardiomyopathy has been reported [8][9][10].…”

Section: Discussionmentioning

confidence: 99%

“…Development of Takotsubo cardiomyopathy, secondary to hyponatremia resulting from prescribed drugs, is well recognized. As with the well-known sequelae of hyponatremia, the rapidity with which the electrolyte disturbance develops is likely to be a deciding factor in the occurrence of Takotsubo cardiomyopathy, as chronic, persistent hyponatremia is a less likely trigger [9]. The mechanism of transient cardiac dysfunction in the setting of hyponatremia, whatever the etiology may be, remains unclear, but this association has been previously observed [10][11][12][13].…”

Section: Discussionmentioning

confidence: 99%

“…The mechanism of transient cardiac dysfunction in the setting of hyponatremia, whatever the etiology may be, remains unclear, but this association has been previously observed [10][11][12][13]. The possible mechanisms proposed are central nervous system dysfunction secondary to hyponatremia, which results in myocardial injury due to raised catecholamine levels, interference of myocardial contractility by low sodium concentration due to disruption of myocyte sodium and calcium exchange, and swelling of cardiac myocytes due to the resultant hypotonicity [9]. The case presented demonstrates the possible association of hyponatremia with stress cardiomyopathy, where the patient made a complete recovery from the cardiac disorder with correction of the electrolyte disturbance.…”

Section: Discussionmentioning

confidence: 99%

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Severe Hyponatremia-Induced Stress Cardiomyopathy: A Case Report and Review of Literature

Rajapakse

Silva

2020

Case Reports in Cardiology

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Takotsubo or stress cardiomyopathy is a non ischemic disease affecting the myocardium, which presents with typical features of myocardial ischemia. Although the presentation with acute central chest pain and shortness of breath mimics acute myocardial ischemia, there is an absence of actual disruption of cardiac blood supply via the coronaries due to acute plaque rupture or vascular spasm. The underlying pathophysiology of this clinical entity remains largely unclear, but a definite association with physical or emotional stress has been well established, hence the term “stress cardiomyopathy.” The list of potential triggers continues to grow as the disorder is increasingly detected by clinicians and cardiologists, with better clinical insight and improved availability of cardiac investigations. We report a patient with Takotsubo cardiomyopathy associated with severe hyponatremia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Severe Hyponatremia-Induced Stress Cardiomyopathy: A Case Report and Review of Literature

Rajapakse

Silva

2020

Case Reports in Cardiology

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“…In six articles, patients presenting with sinus rhythm were described, two of them with the presence of tachycardia 13,15,16,[21][22][23] . T-wave inversion in patients was present in five studies 13,15,17,21 .…”

Section: Clinical Features Of Epileptic Seizures and Electrocardiogra...mentioning

confidence: 99%

“…In nine articles some kind of change in transthoracic echocardiography was reported: seven of them had hypokinesia 13,15,19,20,22 , two akinesia 18,24 , one with posterior wall akinesia and septal wall dyskinesia 25 and two had hyperkinetic basis associated with hypokinesia and/or akinesia 17,21 .…”

Section: Clinical Features Of Epileptic Seizures and Electrocardiogra...mentioning

confidence: 99%

Epilepsy and Takotsubo cardiomyopathy: a scope review

Laguna

Fonseca²,

Mascarenhas³

et al. 2023

Rev Neurocienc

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Introduction. The incidence of sudden death is high in people with chronic epilepsy, especially in the presence of cardiovascular comorbidities, thus, there is a convergence between epilepsy and cardiovascular diseases, however the literature fails on systematic reviews analyzing the interface between epilepsy and Takotsubo cardiomyopathy. Objective. To verify the association between Takotsubo cardiomyopathy and neurological disorders, especially epilepsy. Method. This is a scope review, based on the PRISMA checklist. An advanced and high-sensitivity search was performed using the descriptors "epilepsy" and "Takotsubo cardiomyopathy" combined with the Boolean operator AND, in PubMED, Scientific Electronic Library Online, Portal Regional Biblioteca in Health, and CAPES Periodicals. Results. A total of 373 articles were identified and after applying the eligibility criteria, 14 works were selected to compose the bibliographic sample of this study. It demonstrates the relationship of people with epilepsy developing Takotsubo cardiomyopathy, especially women with advanced age, with comorbidities such as arterial hypertension, diabetes mellitus and hypercholesterolemia, and changes could be evidenced through electrocardiogram and transthoracic echocardiogram. Conclusion. ST-segment depression in the anterior wall and T-wave inversion on the electrocardiogram may suggest Takotsubo cardiomyopathy in people with epilepsy, and this monitoring is important because of the potential for seizures to lead to cardiac conditions. Transthoracic echocardiography is useful for identifying adverse events in people with the comorbidity. Knowledge about epidemiology and the complementary findings described can facilitate clinical reasoning for the diagnosis and management of the condition.

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Reversible Cardiomyopathies

Shah¹,

Rodríguez-Guerra²,

Saad³

et al. 2021

Cardiomyopathy - Disease of the Heart Muscle

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Cardiomyopathy includes a diverse and heterogeneous group of disorders affecting the myocardium and eventually leading to cardiac dysfunction. Cardiomyopathy is the leading cause of hospitalization in patients older than 65 years of age and it is an important cause for enormous healthcare expenditure. All reversible cardiomyopathies can be associated with cardiomegaly, systolic heart failure, structural changes, and an increase in mortality, but when the offensive agent is identified and stopped, these conditions tend to stop their progression and reverse. The prognosis of reversible nonischemic cardiomyopathies is better than ischemic or other nonreversible cardiomyopathies. Additionally, it is important to diagnose etiology of HF early and precisely to determine prognosis and effective treatment. Most patients with reversible cardiomyopathy present with clinical picture similar to that of systolic heart failure. Here in this book chapter, we discuss about different types of reversible cardiomyopathy including pathogenesis, clinical picture, diagnosis and treatment.

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Unusual combined cause of Takotsubo cardiomiyopathy: Hyponatremia and seizure

Cited by 3 publications

References 17 publications

Severe Hyponatremia-Induced Stress Cardiomyopathy: A Case Report and Review of Literature

Severe Hyponatremia-Induced Stress Cardiomyopathy: A Case Report and Review of Literature

Epilepsy and Takotsubo cardiomyopathy: a scope review

Reversible Cardiomyopathies

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