Unusual Case of Extensive Warfarin‐Induced Necrosis in an 84‐Year‐Old

Tillou, X.; Ait-Said, Khalifa; Collon, Sylvie; Desmonts, A.; Bensadoun, H.; Doerfler, A.

doi:10.1111/jgs.12560

Cited by 5 publications

(2 citation statements)

References 6 publications

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“…Breast, buttocks, abdomen, thighs, and calves are more susceptible probably because of the reduced blood supply to adipose tissue. The first case has been reported with breast necrosis [ 7 ] but Verhagen [ 8 ] was the first to describe the association between skin necrosis and oral anticoagulant treatment. Since then, middle-aged, overweight women have been reported in the literature, as cases of skin necrosis resulting from oral anticoagulant treatment [ 1 , 3 ].…”

Section: Discussionmentioning

confidence: 99%

Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope

Bakoyiannis

Karaolanis

Patelis

et al. 2016

Case Reports in Dermatological Medicine

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Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best of our knowledge we present the first case of an old woman diagnosed with warfarin-induced skin necrosis, in whom novel oral anticoagulants and extensive surgical debridement were combined safely with excellent results.

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Section: Discussionmentioning

confidence: 99%

Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope

Bakoyiannis

Karaolanis

Patelis

et al. 2016

Case Reports in Dermatological Medicine

View full text Add to dashboard Cite

show abstract

“…to the Editor scribe WISN in a 52-year-old man with protein C and S deficiency four years after warfarin initiation (5). Tillou et al describe an 84-year-old male with WISN after six months of therapy for PE with DVT (6). Gaikwad et al describe a 31-year-old male with a DVT who presented with WISN after two months of warfarin (7).…”

Section: Lettersmentioning

confidence: 99%