“…Breast, buttocks, abdomen, thighs, and calves are more susceptible probably because of the reduced blood supply to adipose tissue. The first case has been reported with breast necrosis [ 7 ] but Verhagen [ 8 ] was the first to describe the association between skin necrosis and oral anticoagulant treatment. Since then, middle-aged, overweight women have been reported in the literature, as cases of skin necrosis resulting from oral anticoagulant treatment [ 1 , 3 ].…”