Unusual Case of Amiodarone-Induced Thyrotoxicosis “Illicit” use of a Technetium Scan to Diagnose a Transiently Toxic Thyroid Nodule

The usefulness of 99mTc-sestaMIBI thyroid scan in the differential diagnosis and management of amiodarone-induced thyrotoxicosis

“…The faint or transient MIBI uptake observed in AIT Ind may perhaps be explained by incomplete thyroid destruction associated with different degrees of hyperfunctioning tissue. (40). MIBI scintigraphy was also superior to RAIU in the diagnostic evaluation of AIT.…”

Cabozantinib-Induced Thyroid Dysfunction: A Review of Two Ongoing Trials for Metastatic Bladder Cancer and Sarcoma

“…We thus elected to use 99m Tc scans to interrogate the activity of the gland. This tracer enters the thyroid cell via the sodium iodine symporter and it is sensitive and specific for the functional evaluation of the gland (36) and the characterization of amiodarone-induced thyrotoxicosis, which is a classic state of iodine overload (37,38).…”

Thyroid nodule and thyroid cancer management pre- and post-cardiac transplantation

“…11,12 Therefore, these iodine-rich agents cause a predictably low uptake on scans. 13 Interestingly, our patient's I-123 scan result suggested a hot nodule (Figure 2). This is more an exception to the rule and it is unclear how to interpret results in the presence of an iodine load.…”

“…This is more an exception to the rule and it is unclear how to interpret results in the presence of an iodine load. 13,14 A caveat to radioisotope scans is that 18 F-fluorodeoxyglucose (FDG)-PET positive thyroid nodules may be at higher risk for malignancy. 6 However, FDG-PET scans are not currently recommended for the evaluation of thyroid nodules because they cannot consistently distinguish benign from malignant nodules.…”