Unusual Breast Neoplasm with Diagnostic and Management Challenges

Rana, Chanchal; Ramakant, Pooja; Babu, Suresh; Singh, Kulranjan; Mishra, Anand; Mouli, Sasi

doi:10.1007/s13193-018-0781-3

Cited by 3 publications

(2 citation statements)

References 24 publications

(30 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An early diagnosis of breast cancer is very important in the treatment that varies from lumpectomy to mastectomy. This precise diagnosis is mainly essential in the prevention of overtreatment or undertreatment with a poor prognosis (21).…”

Section: Discussionmentioning

confidence: 99%

Correlation Between Ultrasound BI-Rads 4 Breast Lesions and Fine Needle Cytology Categories in a Sample of Iraqi Female Patients

Abdulwahid

Mohammed

Nidhal

et al. 2023

Experimental and Applied Biomedical Research (EABR)

View full text Add to dashboard Cite

Background: Breast cancer is the most common malignancy in female and the most registered cause of women’s mortality worldwide. BI-RADS 4 breast lesions are associated with an exceptionally high rate of benign breast pathology and breast cancer, so BI-RADS 4 is subdivided into 4A, 4B and 4C to standardize the risk estimation of breast lesions. The aim of the study: to evaluate the correlation between BI-RADS 4 subdivisions 4A, 4B & 4C and the categories of reporting FNA cytology results. Patients and Methods: A case series study was conducted in the Oncology Teaching Hospital in Baghdad from September 2018 to September 2019. Included patients had suspicious breast findings and given BI-RADS 4 (4A, 4B, or 4C) in the radiological report accordingly. Fine needle aspiration was performed under the ultrasound guide and the results were classified into five categories. The biopsy was performed for suspicious, malignant or equivocal FNA findings. Results: This study included 158 women with BIRADS 4 breast lesions with the mean age of (44.6 years); There was a highly significant association between BI-RADS 4 breast lesion and FNA results (p<0.001); 51.9% of BI-RADS IV-C had C5 FNA results. There was a highly significant association between BI-RADS 4 lesion and the final diagnosis (p<0.001); 41.2% of BI-RADS 4 B had a malignant breast lesion, while 37.3% of BIRADS 4 C had a malignant lesion. Conclusion: A clear relationship was observed between BI-RADS 4 subcategories and the fine needle aspiration cytology subgroups. BI-RADS 4-B is helpful in the discrimination between benign and malignant breast lesions; furthermore BI-RADS 4C has more acceptable validity in the diagnosis of breast malignancy. Therefore, BI-RADS subcategories are encouraged to be included and mentioned in the ultrasound report for more accurate estimation of the lesion nature.

show abstract

Section: Discussionmentioning

confidence: 99%

Correlation Between Ultrasound BI-Rads 4 Breast Lesions and Fine Needle Cytology Categories in a Sample of Iraqi Female Patients

Abdulwahid

Mohammed

Nidhal

et al. 2023

Experimental and Applied Biomedical Research (EABR)

View full text Add to dashboard Cite

show abstract

“…Early and accurate diagnosis is extremely important to prevent over- or undertreatment with worse outcomes. [7]…”

Section: Introductionmentioning

confidence: 99%

Predictive value of ultrasound imaging in differentiating benign from malignant breast lesions taking biopsy results as the standard

Binnuhaid

Alshoabi

Alhazmi

et al. 2019

J Family Med Prim Care

View full text Add to dashboard Cite

Background:Breast lesions (BLs) are abnormal swellings within the breast. The importance lies in need to exclude breast cancer.Objective:Due to the role of ultrasound (US) imaging in evaluating of BLs, this study was conducted to evaluate the predictive value of US imaging for differentiating benign from malignant BLs and to assess the need of biopsy in BLs.Method:A retrospective review of diagnostic results of 134 patients with BLs. All patients underwent breast US imaging and US-guided biopsy for cytology or histopathology. The results of both were compared.Results:Out of 134 patients were included in this study, the mean age was 38.45 ± 15.82 years (range, 18–90 years), and all patients were female. BLs were benign in 99 cases (73.9%) and malignant in 35 cases (26.1%). Among 98 patients with BLs diagnosed benign with US, 96.9% were confirmed benign with biopsy results and only 3.1% were malignant. The overall sensitivity of US imaging for discriminating of benign BLs was 95.95%, with a specificity of 91.42%, and positive predictive value of 96.94%. The results revealed strong compatibility between diagnoses by US imaging and biopsy results (P < 0.001), the measure of agreement kappa = 0.866, and the Spearman's correlation coefficient = 0.866.Conclusion:US imaging is a highly valuable imaging method in differentiating benign from malignant BLs. It usually predicts the benign nature of BLs with excellent diagnostic accuracy. US-guided fine-needle aspiration and core-needle biopsies are not necessary in most cases of BLs.

show abstract