Untreated syphilis in the male Negro

Schuman, Stanley H.; Olansky, S; Rivers, Eunice; Smith, Clarence A.; Rambo, Dorothy S.

doi:10.1016/0021-9681(55)90153-3

Cited by 70 publications

(7 citation statements)

References 6 publications

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“…For example, regarding the universal denial of penicillin, 2 there are tables in two TSUS articles that list patients who received treatment, including penicillin. 1,26 This compilation of scientific, medical, and historical information will likely equip doctors, other public health professionals, media experts, activists, and the public in their outreach to communities of color. Perhaps one way to mitigate mistrust and promote health in communities of color is to unravel and correct myths about the TSUS.…”

Section: Discussionmentioning

confidence: 99%

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Reaching for Harrison’s and the Tuskegee Study of Untreated Syphilis

White¹

2021

Southern Medical Journal

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T he Tuskegee Study of Untreated Syphilis (TSUS) was the 1932-1972 study of approximately 600 Black men, 400 with active syphilis and 200 presumably without syphilis, in rural Macon County, Alabama. The study evolved from a oneevaluation datapoint to a longitudinal study with detailed case histories and autopsies. These parameters assessed the presence or absence of syphilis-related damage. 1 It ended in scandal in 1972, as reported in the media. 2 The media frequently focuses on race-related disparities with the coronavirus disease 2019 infection-ie, higher prevalence, morbidity, and mortality rates in Black Americans. 3 Blaming the TSUS as the reason for the etiology of disparity-related mistrust in Black communities is common; however, what often is cited about the TSUS is wrong or incomplete, historically, scientifically, and/or medically. 4 This is where an effective medicine textbook, such as Harrison's Principles of Internal Medicine, 5,6 which contains accurate TSUS information, becomes an important tool for doctors and other health professionals to educate, motivate, and recruit communities at risk toward clinical trials, safe and effective treatment, and better health. For 13 editions, Harrison's included the TSUS and the Oslo Study (a nontherapeutic experiment in Norway that also studied untreated syphilis). That much of the information in the public domain about the TSUS is wrong, a brief commentary on the history of Harrison's textbook as it relates to the TSUS and Oslo Study is in order.

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Section: Discussionmentioning

confidence: 99%

“…The study evolved from a one-evaluation datapoint to a longitudinal study with detailed case histories and autopsies. These parameters assessed the presence or absence of syphilis-related damage 1 . It ended in scandal in 1972, as reported in the media 2 …”

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confidence: 99%

Reaching for Harrison’s and the Tuskegee Study of Untreated Syphilis

White¹

2021

Southern Medical Journal

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“… 4 An earlier TSUS article has a table including other patients who received arsenicals and adequate penicillin. 5 It is unknown what information was given to the TSUS participants when they received these treatments. However, the information and/or the treatment experience seemed to be sufficient for subsequent TSUS investigators to decipher the participants’ histories and record the treatments in the tables.…”

Section: To the Editormentioning

confidence: 99%

More on the Tuskegee Study of Untreated Syphilis

White¹

2020

JCO Global Oncology

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“…These hearings put in the forefront several instances of research conducted without any ethical standards in place to protect human participants. Some of the most cited examples are the Tuskegee syphilis study (Schuman, Olansky, Rivers, Smith, Rambo, 1955), the Tearoom trade study (Humphreys, 1970), and the Milgram studies of obedience (Milgram, 1963). The 1974 Act established the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, which in 1978 issued the Belmont Report.…”

Section: Sotl As Human Subjects Researchmentioning

confidence: 99%

SoTL and the Institutional Review Board: Considerations before navigating the application process for classroom research in higher education

Linder

Elek

Calderon

2014

JoSoTL

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One of the more challenging areas of Scholarship of Teaching and Learning (SoTL) research can be navigating the components of human subjects research protections implemented by the Institutional Review Board (IRB). The authors of this article, a faculty developer and a current and former research compliance coordinator, discuss the history of IRB in relation to SoTL research and explicate some of the foundational components of IRB protocols for SoTL projects. In particular, the authors explore what constitutes “research” for SoTL projects, explain the different IRB types of review, and offer some sample SoTL projects with respect to their IRB implications.

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Untreated syphilis in the male Negro

Cited by 70 publications

References 6 publications

Reaching for Harrison’s and the Tuskegee Study of Untreated Syphilis

Reaching for Harrison’s and the Tuskegee Study of Untreated Syphilis

More on the Tuskegee Study of Untreated Syphilis

SoTL and the Institutional Review Board: Considerations before navigating the application process for classroom research in higher education

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