Untersuchungen über Mechanismen der Osmo- und Volumenregulation

Lydtin, H

doi:10.1007/bf02044476

Cited by 12 publications

(1 citation statement)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The renal sympathetic nerve fibres innervate the renal blood vessels (O'Connor, 1962;McKenna & Angelokos, 1968;Pomeranz, Birtch & Barger, 1968;Fourman & Moffat, 1971) and changes in renal blood flow which could result from the inhibition of neural activity may contribute to changes in urine flow. It has been suggested that increased blood flow to the kidney may form part of the reflex response to stimulation of left atrial receptors but the evidence is inadequate (Gauer, Henry & Sieker, 1961;Arndt, Reineck & Gauer, 1963;Lydtin & Hamilton, 1964;Lydtin, 1969). The present results indicate that further studies are needed of the neural as well as humoral factors in the efferent pathway of the diuresis produced by left atrial receptor stimulation.…”

Section: Discussionmentioning

confidence: 78%

The effects of stimulation of the left atrial receptors on sympathetic efferent nerve activity

Karim¹,

Kidd²,

Malpus³

et al. 1972

The Journal of Physiology

215

126

View full text Add to dashboard Cite

SUMMARY1. Activation of left atrial receptors by distension of balloons at the pulmonary vein-atrial junctions caused an increase in the cardiac sympathetic nerve activity, a decrease in the renal sympathetic nerve activity, and no change in the lumbar and splenic sympathetic nerve activity.2. The cardiac and renal nerve responses to balloon distension were abolished by vagal blockade in the neck.3. The results provide additional evidence that the reflex increase in the heart rate following stimulation of the left atrial receptors is mediated by selective activation of cardiac sympathetic nerve fibres.4. The inhibitory effect of atrial receptor activation on the renal sympathetic nerve activity suggests that a neural factor, possibly involving renal haemodynamics, may be a component of the diuretic response to the activation of the left atrial receptors.5. The results provide further evidence for the selective nature of the pattern of reflex responses to left atrial receptor activation and show for the first time a directionally fractionated response from sympathetic efferent neurones.

show abstract

Section: Discussionmentioning

confidence: 78%

The effects of stimulation of the left atrial receptors on sympathetic efferent nerve activity

Karim¹,

Kidd²,

Malpus³

et al. 1972

The Journal of Physiology

215

126

View full text Add to dashboard Cite

show abstract

Comparison of renal responses to 5% saline infusions into vena portae and vena cava in conscious dogs

et al. 1978

View full text Add to dashboard Cite

Vergleichende Untersuchungen zur Wirkung gastroenteraler und parenteraler Kochsalzinfusionen auf die Nierenfunktion nach Hemmung der Prostaglandinsynthese

Heuer

Knue-Beestermüller

1980

Res. Exp. Med.

View full text Add to dashboard Cite

1. a) Studies Without Indomethacin. As compared to infusion of isotonic saline into the stomach water excretion is decreased by 30% (P less than 0.02) and 35% (P = n.s.) in the second and third 90 min period during parenteral infusion of saline. As compared to gastroenteric infusion we found an increase of the total osmolarity by 13% (P less than 0.02) in the cortex of the kidney. b) Studies with Indomethacin. As compared to saline infusion into the stomach indomethacin-treated rats decrease their urinary flow rates in 90 min by 26% (P = n.s.) in the presence of equivalent saline infusion into the aorta. Total osmolarity of the parenteral loaded rats increases by 17% (P less than 0.01) in the cortex of the kidney. 2. Indomethacin leads to an increased concentrating ability of the kidney in both gastroenteric and parenteral loaded rats. 3. In the presence of indomethacin plasma albumin of the kidney increases in the cortex and in the outer medulla of the kidney. In the inner medulla, and in the papillary tip, however, albumin concentration decreases significantly. As compared to gastroenteric saline infusion, the osmolarity of the kidney tissue increases and the urinary flow rate decreases during equivalent parenteral infusion of isotonic saline. The prostaglandins are not responsible for the pronounced diuresis during infusions of isotonic saline into the stomach.

show abstract

Untersuchungen über Mechanismen der Osmo- und Volumenregulation

Cited by 12 publications

References 32 publications

The effects of stimulation of the left atrial receptors on sympathetic efferent nerve activity

The effects of stimulation of the left atrial receptors on sympathetic efferent nerve activity

Comparison of renal responses to 5% saline infusions into vena portae and vena cava in conscious dogs

Vergleichende Untersuchungen zur Wirkung gastroenteraler und parenteraler Kochsalzinfusionen auf die Nierenfunktion nach Hemmung der Prostaglandinsynthese

Contact Info

Product

Resources

About