Untersuchungen über den Synergismus von Giften

Fühner, H.

doi:10.1007/bf01873218

Cited by 44 publications

(2 citation statements)

References 7 publications

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“…Heman George Fühner introduced, for the first time, physostigmine to an organ bath in which a leech muscle was suspended. With this pharmacological tool he was able to tackle the transiency of the effects of ACh and the muscle became extremely sensitive to it (Fühner 1918). For many years the eserinised leech muscle assay remained the most reproducible, sensitive method of identifying and quantifying ACh.…”

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confidence: 99%

Basal Forebrain Cholinergic System and Memory

Blake

Boccia

2016

Current Topics in Behavioral Neurosciences

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Basal forebrain cholinergic neurons constitute a way station for many ascending and descending pathways. These cholinergic neurons have a role in eliciting cortical activation and arousal. It is well established that they are mainly involved in cognitive processes requiring increased levels of arousal, attentive states and/or cortical activation with desynchronized activity in the EEG. These cholinergic neurons are modulated by several afferents of different neurotransmitter systems. Of particular importance within the cortical targets of basal forebrain neurons is the hippocampal cortex. The septohippocampal pathway is a bidirectional pathway constituting the main septal efferent system, which is widely known to be implicated in every memory process investigated. The present work aims to review the main neurotransmitter systems involved in modulating cognitive processes related to learning and memory through modulation of basal forebrain neurons.

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confidence: 99%

Basal Forebrain Cholinergic System and Memory

Blake

Boccia

2016

Current Topics in Behavioral Neurosciences

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“…It is now convenient to distinguish three levels of structure activity relationship: have one or more functional groups and/or fragments in common. It may also result from homologous sets of the type CH 3 (CH 2 ) n Y [8] or from bioisosterism [9,10]. 2.…”

Section: The Dark Ages Of Structure-bioactivity Relationshipsmentioning

confidence: 99%