Untersuchungen über den Kreatin- und Kreatininstoffwechsel. II. Mitteilung. Über das Kreatinin und Kreatin des Blutes.

Zacherl, M. K.; Lieb, Hans

doi:10.1515/bchm2.1934.226.2-3.130

Cited by 7 publications

(1 citation statement)

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“…Other leading scientists supported these conclusions [ 11 ]. The heated controversy then moved from the USA to Europe [ 12 ], where, along with biochemists, clinicians also tackled the issue. Among these emerges the figure who is the subject of our account, the Italian Giovanni Ferro-Luzzi (FL) (1903–2000).…”

Section: The Creatinine Controversymentioning

confidence: 99%

History of creatinine clearance: tribute to a forerunner

Losito

2023

Clinical Kidney Journal

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It is known to few that the path to the discovery of the long-denied plasma creatinine and its clearance was long and difficult. For quite a long time, related controversies between different groups of researchers were widespread and heated. The scientists who have dealt with the related problems are among the most famous of the last century and some of them are part of the history of medicine. Giovanni Ferro-Luzzi (FL), an Italian clinician, was one of these researchers. He was among the first to detect and dose plasma creatinine and the first ever to measure the clearance of endogenous creatinine (CrCl). Unfortunately, due to a series of unforeseeable events, he has been completely forgotten together with his undertakings. In this review we retrace the steps that led to the measurement of plasma creatinine, and CrCl. With brief biographical notes we try to explain the oblivion of this important figure and of his nephrological accomplishments.

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Section: The Creatinine Controversymentioning

confidence: 99%