Untersuchung Des Menschlichen Spermas Auf 17-Ketosteroide

Veld, L. G. Huis in't

doi:10.1530/acta.0.0160257

Cited by 4 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Steroids may be present in seminal plasma [1,5]. In the present studies, the uptake and metabolism of 3H-T occurred in both the epithelium and muscular layers of the vesicular model (table I).…”

Section: Resultssupporting

confidence: 52%

Passage of Substances into the Lumen of the Isolated Seminal Vesicle of the Guinea Pig

Thomas¹,

Mawhinney²,

Lloyd³

et al. 1974

Urol Int

View full text Add to dashboard Cite

The guinea pig seminal vesicle sac preparation is described. The uptake, distribution and secretion of 3–0-methylglucose (3mG), α-amino-isobutyric acid (AIB), testosterone (T) and adenosine (A) were examined following the addition of these substances to the serosal fluid. The findings suggest that AIB is actively transported into the cells of the sex accessory tissues while 3mG enters by the process of simple diffusion. In addition, 3mG readily penetrated into the mucosal fluid, achieving a concentration of approximately one half that detected in the tissue. The uptake and metabolism of testosterone-³H occurred in both the epithelial and muscular layer. Only small amounts of androgen were detected in the mucosal fluid (lumen). Adenosine-³H was detected in near equal concentrations in the epithelial and muscular layers. Little adenosine-³H reached the lumen of the vesicular model. The in vitro bioconversion of adenosine-³H to cAMP-³H revealed equal distribution of this cyclic nucleotide in the epithelial and muscular layers of the seminal vesicle. Substantial amounts of cAMP-³H were found in the lumen of the in vitro preparation.

show abstract

Section: Resultssupporting

confidence: 52%

Passage of Substances into the Lumen of the Isolated Seminal Vesicle of the Guinea Pig

Thomas¹,

Mawhinney²,

Lloyd³

et al. 1974

Urol Int

View full text Add to dashboard Cite

show abstract

“…Testosterone given during and after operation has not been found to influence the postoperative rise in the urinary excretion of corticosteroids (Edwards, Jepson, and Reece, 1957). Norethandrolone and methandienone reduce the urinary excretion of corticosteroids in resting patients (Brooks and Prunty, 1957;Wynn, Landon, and James, 1962)~ but neither these nor various other anabolic steroids affect the adrenocortical response to exogenous corticotrophin (Huis in't Veld, Louwerens, and van der Spek, 1960;Wynn and others, 1962). Testosterone and anabolic steroids have, among other properties, a sodium-retaining effect when given to resting subjects, and this might well accentuate the normal postoperative retention of sodium.…”

Section: Introductionmentioning

confidence: 99%