“…Syntheses have been reported for nicotine (220,221,320), nicotine analogs (156,613), myosmine (220), N-methylmyosmine (320), and anatabine (434). The autooxidation of nicotine apparently occurs through a free-radical mechanism (313); although hydroperoxides have not been isolated from the oxidative products, myosmine, nicotyrine, cotinine, nicotine N-oxide, nicotinic acid, and possibly high molecular weight components occur therein (176,598).…”