“…Natural products bearing a trisulfide bridge have been attractive and challenging targets for synthetic campaigns, exemplified by the total synthesis of calicheamicin γ 1 ( 2 ) by Nicolaou and co-workers in 1992 and of luteoalbusins by Movassaghi and co-workers in 2015 . Trisulfide bridge-containing natural products, such as luteoalbusin B ( 3 ), (2 E ,4′ R ,5′ S ,6′ S ,7′ R )-3-{7′-hydroxy-4′,6′-dimethyl-4′-(3″-methylenepent-4″-enyl)[1′,2′,3′]trithiocan-5′-yl} acrylic acid ( 4 ), cis -5-hydroxy-4-(4′-hydroxy-3′-methoxyphenyl)-4-(2″-imidazolyl)-1,2,3-trithiane ( 5 ), and a psammaplin congener ( 6 ) (Figure ), therefore continue to inspire innovations in synthetic organic chemistry. − , …”