Unripe Musa sapientum peel in the healing of surgical wounds in rats

Atzingen, Dênia Amélia Novato Castelli Von; Gragnani, Alfredo; Veiga, Daniela Francescato; Abla, Luis Eduardo Felipe; Cardoso, Lorraine Lorene Felix; Ricardo, Thiago; Mendonça, Adriana Rodrigues dos Anjos; Ferreira, Lydia Masako

doi:10.1590/s0102-86502013000100006

Cited by 12 publications

(9 citation statements)

References 11 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile, saponin (24 mg/g) has also been found in Musa sapientum peels (Anhwange, 2008). Unripe banana peel has been shown to contain leucocyanidin, a fl avonoid that helps in accelerating the healing of skin wounds as well as surgery wounds (Atzingen et al, 2013). The antioxidative effi cacy of unripe banana peel has been shown effective in the prevention and treatment of peptic ulcers in rat model.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant effcacy of unripe banana (Musa acuminata Colla) peel extracts in sunflower oil during accelerated storage

Ling¹,

Chang²,

Sia³

et al. 2015

Acta Sci Pol Technol Aliment

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Antioxidant effcacy of unripe banana (Musa acuminata Colla) peel extracts in sunflower oil during accelerated storage

Ling¹,

Chang²,

Sia³

et al. 2015

Acta Sci Pol Technol Aliment

View full text Add to dashboard Cite

“…The treatment with the banana tree was less painful, as well as healing occurred in a shorter time, demonstrating as a therapeutic action the healing effect on wounds of the banana leaf in a skin graft donor area [17]. In addition to the banana leaves, the 4% gel of the M. sapientum green bark also promoted a greater epithelization area in wound healing with second intention in rats [9], showing the diversity of therapeutic actions that come from Of the banana, its bark, the leaves of the banana tree, and its derivatives.…”

Section: Discussionmentioning

confidence: 92%

“…In addition to its highly antioxidant power, this fruit also presents other important functions such as the gel to 4% of its bark, which promoted a great area of epithelialization in wound healing with second intention in rats [9]. The use of the 4% banana gel in surgical incisions in rats also has repercussion in reducing the area of the lesion, reducing vascular proliferation and increasing collagen concentration in the wound [10].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Action and Scaring of 10% Green Banana Shell in Chronic Wounds

Loyola¹,

Fernandes²,

Mendes³

et al. 2018

OJMM

Self Cite

View full text Add to dashboard Cite

The percentage of diabetic patients with contaminated lesions increases from 3% to 10%. Treatment with herbal products shows benefits in their use, as well as antioxidant and antifungal activities. Objective: to evaluate the antimicrobial action of 10% banana peel gel and the contraction of diabetic and venous wounds. Methods: individual, analytical, interventional, longitudinal, prospective, randomized study from February to December 2015. Five patients were included in the study; 3 with venous ulcer and 2 with diabetic wound. Application of 10% green banana peel gel and weekly samples were performed. After six days, the second collection was performed. The samples were seeded in the Mannitol salt agar culture medium, MacConkey agar and Saboraund agar with chloramphenicol for isolation of cocci and Gram-positive and Gram-negative bacilli; and fungi. The total counts of bacteria were determined by PCA (Plate Count Agar) and measurement of the lesion margin. There was a reduction of microorganisms with the use of the gel in 53.57% of the patients, and reduction of wound areas in 48.1%.

show abstract

“…The four lactobacilli strains were incorporated into natrosol gels, a hydroxyethyl cellulose-based formulation with a suitable consistency and pH for application on the skin that has been used for the development of healing products [ 34 , 35 ]. In addition, the osmotic properties of a hydroxyethyl cellulose-based formulation allow it to absorb the liquids released from the wounded tissues [ 36 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

Development and Characterization of Hydroxyethyl Cellulose-Based Gels Containing Lactobacilli Strains: Evaluation of Antimicrobial Effects in In Vitro and Ex Vivo Models

et al. 2023

View full text Add to dashboard Cite

This study aimed to develop a hydroxyethyl cellulose-based topical formulation containing probiotics and to evaluate its antimicrobial action using in vivo and ex vivo models. Initially, the antagonistic effects of Lacticaseibacillus rhamnosus ATCC 10863, Limosilactobacillus fermentum ATCC 23271, Lactiplantibacillus plantarum ATCC 8014 and Lactiplantibacillus plantarum LP-G18-A11 were analyzed against Enterococcus faecalis ATCC 29212, Klebsiella pneumoniae ATCC 700603, Staphylococcus aureus ATCC 27853 and Pseudomonas aeruginosa ATCC 2785. The best action was seen for L. plantarum LP-G18-A11, which presented high inhibition against S. aureus and P. aeruginosa. Then, lactobacilli strains were incorporated into hydroxyethyl cellulose-based gels (natrosol); however, only the LP-G18-A11-incorporated gels (5% and 3%) showed antimicrobial effects. The LP-G18-A11 gel (5%) maintained its antimicrobial effects and viability up to 14 and 90 days at 25 °C and 4 °C, respectively. In the ex vivo assay using porcine skin, the LP-G18-A11 gel (5%) significantly reduced the skin loads of S. aureus and P. aeruginosa after 24 h, while only P. aeruginosa was reduced after 72 h. Moreover, the LP-G18-A11 gel (5%) showed stability in the preliminary and accelerated assays. Taken together, the results show the antimicrobial potential of L. plantarum LP-G18-A11, which may be applied in the development of new dressings for the treatment of infected wounds.

show abstract

Unripe Musa sapientum peel in the healing of surgical wounds in rats

Abstract: The use of 4% unripe Musa sapientum peel gel on surgical wounds in rats resulted in an increased number of polymorphonuclear cells on day 7, reduced wound contraction, reduced vascular proliferation and increased concentration of collagen fibers on day 21.

Cited by 12 publications

References 11 publications

Antioxidant effcacy of unripe banana (Musa acuminata Colla) peel extracts in sunflower oil during accelerated storage

Antioxidant effcacy of unripe banana (Musa acuminata Colla) peel extracts in sunflower oil during accelerated storage

Antimicrobial Action and Scaring of 10% Green Banana Shell in Chronic Wounds

Development and Characterization of Hydroxyethyl Cellulose-Based Gels Containing Lactobacilli Strains: Evaluation of Antimicrobial Effects in In Vitro and Ex Vivo Models

Contact Info

Product

Resources

About