Unreported anatomical variation of septum pellucidum

Abstract

During gross anatomy dissections of the brain, a developmental abnormality of the septum pellucidum was found in a 31‐year‐old male cadaver. Other parts of the central nervous system in this cadaver were normal in every aspect. Histological samples were taken from the neighboring areas of this abnormality, and they were examined under light microscope and scanning electron microscope. In this abnormality of the septum pellucidum, the two laminae of the septum pellucidum were fused together and there was a hole located 1 cm anterior to its apex. The maximum diameter of the hole was 0.5 cm in the sagittal plane and 0.6 cm in the vertical plane. In the light microscopic and scanning electron microscopic examinations, the free margin of this foramen was regular, and the surrounding tissue was intact and histologically unique to the septum pellucidum. Ependymal cells were present at the free margin of the foramen. Cavum vergae, cavum septum pellucidum, and agenesis of the septum pellucidum are described in the literature. These three abnormalities are seen in cadavers usually with histories of schizophrenia and other psychiatric or neurologic disorders. In a retrospective study, the cadaver with this abnormality had a history of schizophrenia and no history or signs of any kind of brain or head operation. As far as we could ascertain, the abnormality described here has not been reported previously. Clin. Anat. 10:245–249, 1997. © 1997 Wiley‐Liss Inc.

Cavum Septum Pellucidum: Hallazgo Mediante Disección Neuroanatómica

“…Este espacio cerrado (Testut & Latarjet;Kuhlenbeck, 1973) es de variadas dimensiones y no comunica con los ventrículos laterales (Testeut & Latarjet;Clemente, 1985;Kuhlenbeck;Kiernan, 2009;Aldur et al, 1997) o con el espacio subaracnoideo (Kiernan, Duque Parra, 2002). Su forma es trigonal de base anterior y vértice posterior, sus láminas se unen cranealmente a la superficie cóncava inferior del tronco, rodilla y pico del cuerpo calloso.…”