Unreliability of the oral iron absorption test

Lanzkowsky, Philip; Karayalcin, Gungor; Betkerur, Umesh; Shende, Ashok

doi:10.1016/s0022-3476(77)80730-0

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…This study also indicates that control of disease activity is essential if a subject with active inflammation is to respond to oral iron supplementation. Further work is necessary to determine whether the oral iron absorption test and serum IL‐6 level can predict a priori which IBD subjects will respond to iron supplementation and whether higher doses of ferrous sulfate can overcome the reduced absorption seen with the dose used in this study, as suggested by Lanzkowsky et al35 in children without IBD. Additional limitations of our study were the small sample size, lack of repeated measures, potential variations in the timing of urine processing, and the wide standard deviation in PCDAI among patients with active disease 20…”

Section: Discussionmentioning

confidence: 94%

Impaired intestinal iron absorption in Crohnʼs disease correlates with disease activity and markers of inflammation

Semrin

Fishman

Bousvaros

et al. 2006

Inflammatory Bowel Diseases

159

120

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Background-Anemia in patients with Crohn's disease (CD) is a common problem of multifactorial origin, including blood loss, mal-absorption of iron, and anemia of inflammation. Anemia of inflammation is caused by the effects of inflammatory cytokines [predominantly interleukin-6 (IL-6)] on iron transport in enterocytes and macrophages. We sought to elucidate alterations in iron absorption in pediatric patients with active and inactive CD.

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Section: Discussionmentioning

confidence: 94%

Impaired intestinal iron absorption in Crohnʼs disease correlates with disease activity and markers of inflammation

Semrin

Fishman

Bousvaros

et al. 2006

Inflammatory Bowel Diseases

159

120

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Intestinal 59Fe distribution and absorption in rats with different iron status and given wheat bran or ferrous sulfate as dietary iron sources

Buchowski

Mahoney

1992

Nutrition Research

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The Laboratory Evaluation of Microcytic Red Blood Cells

Marsh¹,

Koenig²

1982

CRC Critical Reviews in Clinical Laboratory Sciences

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Microcytic red blood cell states are common clinical problems in both adult and pediatric age groups. The recent widespread availability of electronic blood cell counters for performing routine blood counts has increased the detection of microcytic red blood cells. Physicians must workup both symptomatic and asymptomatic patients with microcytic red blood cells before they can initiate proper therapy and/or counseling. The purpose of this review is threefold: (1) to discuss the causes of microcytic red blood cells in terms of disorders of decreased heme production vs. disorders of decreased globin production, (2) to review the clinical laboratory tests useful in differentiating microcytic red blood cell states, and (3) to present a practical approach for the laboratory workup of microcytic red blood cells.

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Unreliability of the oral iron absorption test

Cited by 3 publications

References 4 publications

Impaired intestinal iron absorption in Crohnʼs disease correlates with disease activity and markers of inflammation

Impaired intestinal iron absorption in Crohnʼs disease correlates with disease activity and markers of inflammation

Intestinal 59Fe distribution and absorption in rats with different iron status and given wheat bran or ferrous sulfate as dietary iron sources

The Laboratory Evaluation of Microcytic Red Blood Cells

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