Unregulated use of clobetasol propionate

Keane, Fergus; Munn, S.E.; Taylor, Nicholas; Vivier, Anthony du

doi:10.1046/j.1365-2133.2001.04213.x

Cited by 23 publications

(22 citation statements)

References 12 publications

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“…Acne was the most common indication of steroid application; hence, the predominance of younger age group in our study is easily explained and this is also reported in a study by Manchanda et al [12] Most of the subjects were using potent TCs in our study, which is in concordance with prior studies from other countries. [13] Betamethasone alone or in combination was by far the most common corticosteroid used by our patients and same has been reported by Sharma et al [4] BETNOVATE, PANDERM and CLOBEN-G were the commonly misused brand names. Mometasone, hydroquinone and tretinoin containing skin-lightening formulas are very popular and very easily available in the market.…”

Section: Discussionsupporting

confidence: 60%

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Chauhan¹

2017

jmscr

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Section: Discussionsupporting

confidence: 60%

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Chauhan¹

2017

jmscr

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“…These include effects on the epidermis and the dermis in addition to those resulting from their systemic absorption. [789101112]…”

Section: Discussionmentioning

confidence: 99%

Misuse of topical corticosteroids: A clinical study of adverse effects

Dey

2014

Indian Dermatol Online J

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Background:Misuse of topical corticosteroids is a widespread phenomenon among young people in India, especially women. The practice is associated with significant adverse effects and poor awareness of these effects among the general public.Aim:This study was conducted to examine the misuse and adverse effects of topical corticosteroids among the people in Bastar region in Chhattisgarh state of India.Materials and Methods:Data collected from patients presenting with at least one of the adverse effects of topical corticosteroids as the chief complaint, from November 2010 to October 2011.Results:Out of the 6723 new patients, 379 (5.63%) had presented with misuse and adverse effects of topical corticosteroids, of whom 78.89% were females. More than 65% of the patients were in the age group 10-29 years. The main reason for using the topical corticosteroids was to lighten skin colour and treat melasma and suntan. Acne (37.99%) and telangiectasia (18.99%) were the most common adverse effects noted.Conclusions:Misuse of topical corticosteroids has a huge impact on dermatological practice, leading to a significant proportion of visits to the dermatologist. This hydra-headed problem needs multi-dimensional interventions, involving educational, legal and managerial approaches with cooperation from different sectors of society.

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“…12,13 As a result of a lack of understanding about the appropriate use of depigmenting agents, coupled with negative cultural perceptions about dark skin, these cutaneous depigmenting agents may be subsequently intentionally or inadvertently misused. 14,15 Prevalence of skin bleaching A review of the scientific literature demonstrates that individuals from diverse communities around the world, including Africa, North America, Europe, Asia and the Middle East practice skin bleaching. Evidence from the non-medical press further highlights the global burden of this practice.…”

Section: Introductionmentioning

confidence: 99%

Skin bleaching: highlighting the misuse of cutaneous depigmenting agents

Dadzie

Petit

2009

Acad Dermatol Venereol

130

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Hydroquinone and other cutaneous depigmenting agents are widely used by dermatologists to treat pigmentary disorders. On 29 August 2006, the US Food and Drug Administration (FDA) published a monograph in the US Federal Register proposing to ban all hydroquinone products that have not been approved via a New Drug Application process. Reports in the scientific literature on the occurrence of exogenous ochronosis, in relation to the use of hydroquinone, was one of the concerns expressed by the FDA in relation to this agent. However, a review of the English-language scientific literature reveals that most of the reported cases of hydroquinone-induced exogenous ochronosis occurs in Africa, where the cultural practice of skin bleaching is highly prevalent. Skin bleaching is the practice of applying hydroquinone and/or other depigmenting agents to specific or widespread areas of the body, the primary function being to lighten normally dark skin. This practice typically occurs in men and women with Fitzpatrick skin phototypes IV to VI. It is a dangerous practice associated with a diverse range of side-effects, including mercury poisoning. Thus, this current discussion within the dermatological community on the safety of hydroquinone provides a unique opportunity to raise awareness about skin bleaching.

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Unregulated use of clobetasol propionate

Cited by 23 publications

References 12 publications

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Topical Corticosteroids - A Great Challenge to Avoid Misuse on Face

Misuse of topical corticosteroids: A clinical study of adverse effects

Skin bleaching: highlighting the misuse of cutaneous depigmenting agents

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