Abstract:Background:
Sleep is an indispensable phenomenon in almost every organism’s life. Sleep deprivation (SD) caused by professional demands or lifestyle causing low grade neuroinflammation resulting in physiological and cognitive deficits. However, the impact of neuroinflammation on hippocampal circuitry during sleep deprivation is well-documented, but the temporal events triggering neuroinflammation during SD in the dorsal hippocampus and its effects on fear extinction memory requires further investigation.
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