Unravelling the Complexity of HNSCC Using Single-Cell Transcriptomics
Cristina Conde-Lopez,
Divyasree Marripati,
Moshe Elkabets
et al.
Abstract:Background/Objectives: Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous and the most common form of head and neck cancer, posing significant challenges for disease management. The objective of this review is to assess the utility of single-cell RNA sequencing (scRNAseq) in addressing these challenges by enabling a detailed characterization of the tumor microenvironment (TME) at the cellular level. Methods: This review compiles and analyzes current strategies that utilize scRNAseq and oth… Show more
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