Unraveling the role of oxytocin in the motivational structure of conflict

Hurlemann, René; Marsh, Nina

doi:10.1017/s0140525x19000785

Cited by 3 publications

(3 citation statements)

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“…These factors could modify the modulatory effects of oxytocin on social behaviors (Van IJzendoorn et al, 2011;Declerck et al, 2020;Marsh et al, 2021). For instance, contextual information associated with danger or social threat can stimulate oxytocin release that can be associated with aggressive-defensive or antisocial behaviors (Hurlemann and Marsh, 2019). Dysregulation or malfunctioning of the oxytocin system has been reported in neuropsychiatric (Green et al, 2001;Yamasue and Domes, 2017;Goh et al, 2021) and neurodegenerative disorders (Gabery et al, 2015;Unti et al, 2018), mostly in the form of reduced endogenous oxytocin levels.…”

Section: Translating Animal Models: From Endogenous System To Oxytoci...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Dissecting social decision-making: A spotlight on oxytocinergic transmission

Coccia

Greca

Luca

et al. 2022

Front. Mol. Neurosci.

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Social decision-making requires the ability to balance both the interests of the self and the interests of others to survive in social environments. Empathy is essential to the regulation of this type of interaction, and it often sustains relevant prosocial behaviors such as altruism and helping behavior. In the last decade, our capacity to assess affective and empathy-like behaviors in rodents has expanded our understanding of the neurobiological substrates that underly social decision-making processes such as prosocial behaviors. Within this context, oxytocinergic transmission is profoundly implicated in modulating some of the major components of social decision-making. Thus, this review will present evidence of the association between oxytocin and empathy-like and prosocial behaviors in nonhuman animals. Then, we will dissect the involvement of oxytocinergic transmission—across different brain regions and pathways—in some of the key elements of social decision-making such as emotional discrimination, social recognition, emotional contagion, social dominance, and social memory. Evidence of the modulatory role of oxytocin on social decision-making has raised considerable interest in its clinical relevance, therefore we will also discuss the controversial findings on intranasal oxytocin administration.

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Section: Translating Animal Models: From Endogenous System To Oxytoci...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Dissecting social decision-making: A spotlight on oxytocinergic transmission

Coccia

Greca

Luca

et al. 2022

Front. Mol. Neurosci.

View full text Add to dashboard Cite

show abstract

“…Altruistic and hostile behaviors are often viewed as diametrically opposed. In fact, due to variability in individual, motivational, and situational factors, aggression and conflict may not be exclusively linked to antisocial motivations, in the same way as altruism may not exclusively result from prosocial motivations (Hurlemann and Marsh 2019;Marsh 2018a). In-group favoritism represents a form of altruism, which may result in hostile behaviors toward the out-group or other manifestations of pathological altruism.…”

Section: Conflictmentioning

confidence: 99%

Oxytocin and the Neurobiology of Prosocial Behavior

Marsh

Lee

et al. 2020

Neuroscientist

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Humans are an unusually prosocial species, who engage in social behaviors that include altruism—whereby an individual engages in costly or risky acts to improve the welfare of another person—care, and cooperation. Current perspectives on the neurobiology of human prosociality suggest that it is deeply rooted in the neuroendocrine architecture of the social brain and emphasize the modulatory role of the neuropeptide hormone oxytocin. In this review, we provide a conceptual overview of the neurobiology of prosocial behavior with a focus on oxytocin’s modulatory role in human prosociality. Specifically, we aim to encourage a better understanding of the peptide’s susceptibility to diverse factors that produce heterogeneity in outcomes and the resulting methodological implications for measuring the behavioral effects of oxytocin in humans. After providing an overview of the state-of-the-art research on oxytocin’s exogenous use, we elaborate on the peptide’s modulatory role in the context of care-based altruism, cooperation, and conflict and discuss its potential for therapeutic interventions in psychiatric disorders characterized by social dysfunction.

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Evolution of human language: duetting as part of prosociality and cognition

Kaplan

2023

Front. Ecol. Evol.

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The evolution of human language is a topic that has received undiminished attention. Numerous hypotheses for the origin of human language have been proposed, including gestural communication found specifically among apes. This study advances the hypothesis that human evolution, including human language development, is three-pronged: prosocial, cognitive, and collaborative. Duetting and turn-taking in primates are used as pivotal examples of how bonding leads to joint action and collaboration. It points out that such vocal behavior itself may be a crucial precursor of language evolution in the sense that it is explicitly focused on a conspecific. Some current hypotheses have acknowledged duetting as an important perceptual and behavioral example of synchronicity. Some forms of synchronized behavior, as found in duetting, synchronized dance, or even shared song, were perhaps crucial evolutionary steps preceding the evolution of human language. Duetting signifies more than that, however, because it is an observable and significant cognitive investment that signals attention toward a partner. This study also advances the hypothesis that affect and cognition would have needed to precede any form of duetting or signs of affiliation such as grooming. Hence, this study, asking what duetting in primates signifies in evolutionary terms, takes a multidisciplinary and multimodal approach to suggest important affective and cognitive steps in the evolution of human language and speech, the chief of which is prosociality. Prosociality, as an attitude and awareness of another, be this as a friend or partner for whom one can do favors or whom one can help, is a model for collaboration and cooperation, and also increased cognition.

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Unraveling the role of oxytocin in the motivational structure of conflict

Cited by 3 publications

References 60 publications

Dissecting social decision-making: A spotlight on oxytocinergic transmission

Dissecting social decision-making: A spotlight on oxytocinergic transmission

Oxytocin and the Neurobiology of Prosocial Behavior

Evolution of human language: duetting as part of prosociality and cognition

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