Unraveling the relationship between the renin–angiotensin system and endometrial cancer: a comprehensive review
Nihad Ashraf Khan,
Deena Elsori,
Gowhar Rashid
et al.
Abstract:Endometrial cancer (EC), the most common adenocarcinoma, represents 90% of uterine cancer in women with an increased incidence of occurrence attributed to age, obesity, hypertension, and hypoestrogenism. Being the most common gynecological malignancy in women, it shows a relation with the activation of different components of the renin–angiotensin system (RAS), which is predominantly involved in maintaining blood pressure, salt, water, and aldosterone secretion, thereby playing a significant role in the etiolo… Show more
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