Unraveling the Power of Topical Inhaled Steroids in Treating Laryngeal Granulomas: A Systematic Review

Abstract

The efficacy of inhaled steroids in the treatment of airway laryngeal granuloma is an important topic of research, given the increasing prevalence of this condition. In this systematic review, we aimed to evaluate the existing evidence on the effectiveness of inhaled steroids in treating airway granuloma. The search was performed in several electronic databases including PubMed, Embase, and the Cochrane Library. We included all relevant studies that were published in the English language between 2005 and 2021. A total of nine studies were eligible for inclusion in our systematic review, including one randomized controlled trial, one case-control study, and seven retrospective studies. The results of our review suggest that inhaled steroids may be effective in treating airway granuloma, but more research is needed to confirm these findings. The limitations of the included studies, such as small sample sizes, inconsistent study designs, and a lack of long-term follow-up, suggest that additional research is needed to confirm the effectiveness of inhaled steroids in treating airway granuloma. Overall, this systematic review highlights the need for further studies to confirm the effectiveness of inhaled steroids in treating airway granuloma.

A Case Report of Juvenile-Onset Recurrent Respiratory Papillomatosis

“…Yet no previous studies have found an association between PPI and the efficacy of nebulized Ciprodex in postoperative JORRP. However, there is a study that showed using inhaled corticosteroids and PPIs immediately postoperatively following airway surgery is effective in preventing granulation tissue formation and protecting the airway from reflux, which can worsen the voice after surgery [8]. Tracheostomy is reserved for cases of acute airway obstruction and aggressive RRP.…”