Abstract:Viral infection relies on the hijacking of cellular machineries to enforce the reproduc- tion of the infecting virus and its subsequent diffusion. In this context the replication of the viral genome is a key step performed by specific enzymes, i.e. polymerases. The replication of SARS-CoV-2, the causative agent of the COVID-19 pandemics, is based on the duplication of its RNA genome, an action performed by the viral RNA- dependent-RNA polymerase. In this contribution, for the first time and by using two- dimen… Show more
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