Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications
Raquel de Oliveira Souza,
José Wandilson Barboza Duarte Júnior,
Victória Simões Della Casa
et al.
Abstract:Arthritogenic alphaviruses pose a significant public health concern due to their ability to cause joint inflammation, with emerging evidence of potential neurological consequences. In this review, we examine the immunopathology and immune evasion strategies employed by these viruses, highlighting their complex mechanisms of pathogenesis and neurological implications. We delve into how these viruses manipulate host immune responses, modulate inflammatory pathways, and potentially establish persistent infections… Show more
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