“…Various methodological approaches have been developed over the last decades to unravel the morphological features of neurons and their diversity, forming the anatomical architecture of the mammalian brain (Bowman & Frankfurt, 2021; Lanciego & Wouterlood, 2011, 2020; Zeng, 2021). At the same time, dendritic spines have been described as multifunctional postsynaptic units that reflect cellular connectivity and enable multiple ways for function and plasticity in neurons (Chen & Sabatini, 2012; Cornejo et al., 2022; Hayashi‐Takagi et al., 2015; Helm et al., 2021; Rasia‐Filho, 2022; Rochefort & Konnerth, 2012; Spruston et al., 2013; Tønnesen and Nägerl, 2016; Yuste, 2010). However, the study of human dendrites and spines continues to be challenging due to the high complexity of the nervous tissue in our species (Shapson‐Coe et al., 2021) and some technical difficulties in the histological processing of postmortem samples (Dall´Oglio et al., 2015; Vásquez et al., 2018), although there has been excellent progress in characterizing neurons in acute slices from neurosurgical resections (Berg et al., 2021; Molnar et al., 2016; Planert et al., 2021).…”