2012
DOI: 10.4187/respcare.02164
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Unplanned Extubation in the Neonatal ICU: A Systematic Review, Critical Appraisal, and Evidence-Based Recommendations

Abstract: SummaryOBJECTIVE: To update the state of knowledge on unplanned extubations (UEs) in neonatal ICUs. This review focuses on the following topics: incidence, risk factors, reintubation after UE, outcomes, and prevention. METHODS: The MEDLINE, EMBASE, CINAHL, Scielo, Lilacs, and Cochrane databases were searched for relevant publications from January 1, 1950, through January 30, 2012. Fifteen articles were selected for data abstraction. The search strategy included the following key words: "unplanned extubation," … Show more

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Cited by 85 publications
(131 citation statements)
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References 23 publications
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“…15 Although it may seem intuitive that restraining patients might prevent self-extubations, the rate of patients in restraints at the time of unplanned extubation is roughly 60%. 10,15,16,20 This suggests that restraints do not prevent self-extubation. Moreover, they can contribute to agitation, 10 and are discouraged unless necessary due to other safety concerns.…”
Section: Unplanned Extubationsmentioning
confidence: 99%
See 1 more Smart Citation
“…15 Although it may seem intuitive that restraining patients might prevent self-extubations, the rate of patients in restraints at the time of unplanned extubation is roughly 60%. 10,15,16,20 This suggests that restraints do not prevent self-extubation. Moreover, they can contribute to agitation, 10 and are discouraged unless necessary due to other safety concerns.…”
Section: Unplanned Extubationsmentioning
confidence: 99%
“…7,11,13 Approximately 50% of these patients will require re-intubation (range of 10 -78%). [6][7][8]11,13,15,16 Based upon the literature, successful strategies for the prevention of unplanned extubations include standardized protocols for securing the tracheal tube, 15,[17][18][19][20] titration of sedation, [15][16][17]21 weaning patients off mechanical ventilation, 16,20 tube suctioning, patient hygiene, and transport. 15 Although it may seem intuitive that restraining patients might prevent self-extubations, the rate of patients in restraints at the time of unplanned extubation is roughly 60%.…”
Section: Unplanned Extubationsmentioning
confidence: 99%
“…Risk factors included age \2 years, agitation, increased saliva, increased duration of ventilation Silva et al [10] Systematic review 2013 Neonates 0.14-5.3 per 100 intubation days Lucas da Silva et al [11] Systematic review 2010 Pediatric 0.11-2.27 per 100 intubation days Piva et al [12] Prospective observational …”
Section: Referencesmentioning
confidence: 99%
“…[1][2][3] Unplanned extubations are relatively frequent, representing the fourth most common adverse event in North American NICUs. 4 The incidence of unplanned extubations in the NICU ranges from 1% to 80%, [5][6][7][8] and the rate of unplanned extubations ranges from 0.14 to 6.6 per 100 patient-intubated days. 1,2,5,7,8 Compared with data from PICUs, unplanned extubations in neonatal patients occur 2 to 3 times more frequently.…”
mentioning
confidence: 99%
“…4 The incidence of unplanned extubations in the NICU ranges from 1% to 80%, [5][6][7][8] and the rate of unplanned extubations ranges from 0.14 to 6.6 per 100 patient-intubated days. 1,2,5,7,8 Compared with data from PICUs, unplanned extubations in neonatal patients occur 2 to 3 times more frequently. 9 Potential reasons for this increased incidence include longer duration of intubation, shorter length of the trachea in neonates compared with older children, the use of uncuffed endotracheal tubes in neonates, and less routine use of sedation and muscle relaxation, as well as time spent out of bed while being held by parents.…”
mentioning
confidence: 99%