Unpinning of pinning sprial waves with pulses of radial electrical field

Abstract

In this paper, the process of unpinning spiral waves from obstacles with Pulses of Radial Electrical Field (PREF) in excitable medium is studied using Barkley model. We used a radial electrical field to simulate the field of an needle electrode placed in the middle of a round obstacle. Numerical results show that the PREF can separate spiral waves from obstacles effectively. With a Single Pulse of Radial Electrical Field (SPREF), spiral waves could be unpinned from an obstacle effectively in a weakly excitable medium, but it could not be unpinned in a strongly excitable medium. The unpinning parameter space of a SPREF is larger than that of a Uniform Electric Field or Anti-tachycardia Pacing. Multiple Pulses of Radial Electrical Field (MPREF) is effective for unpinning in the entire parameter space that spiral waves exist. Comparing with other methods to unpin spiral waves, the PREF method has the advantages of low electric field magnitude, high success rate and large applicating range in the parameters space. And differ from other methods, the success rate of PREF is not sensitive to the phase of the spiral wave on the obstacle. We hope that this method will provide a new idea for clinical treatment for related cardiac diseases.