Unnatural Nucleosides with Unusual Base Pairing Properties

Bergstrom, Donald E.

doi:10.1002/0471142700.nc0104s37

Cited by 7 publications

(1 citation statement)

References 194 publications

(232 reference statements)

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“…Although excluded from the current RNAMDB, non-natural modifications are gaining increasing interest in both academic and corporate settings. These types of modifications include those used as research tools because of their ability to fluoresce (36), to restrict certain geometries, including backbone alterations (37), to enable unusual base pairing schemes (38) and to act as tools for probing structure (39,40). Furthermore, other non-natural nucleosides that have been discovered as the products of interactions with pharmaceuticals and as a result of environmental stimuli will be also included.…”

Section: The Rna Institute Takes Over As Curatormentioning

confidence: 99%

The RNA modification database, RNAMDB: 2011 update

Cantara

Crain

Rozenski

et al. 2010

Nucleic Acids Research

733

754

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Since its inception in 1994, The RNA Modification Database (RNAMDB, http://rna-mdb.cas.albany.edu/RNAmods/) has served as a focal point for information pertaining to naturally occurring RNA modifications. In its current state, the database employs an easy-to-use, searchable interface for obtaining detailed data on the 109 currently known RNA modifications. Each entry provides the chemical structure, common name and symbol, elemental composition and mass, CA registry numbers and index name, phylogenetic source, type of RNA species in which it is found, and references to the first reported structure determination and synthesis. Though newly transferred in its entirety to The RNA Institute, the RNAMDB continues to grow with two notable additions, agmatidine and 8-methyladenosine, appended in the last year. The RNA Modification Database is staying up-to-date with significant improvements being prepared for inclusion within the next year and the following year. The expanded future role of The RNA Modification Database will be to serve as a primary information portal for researchers across the entire spectrum of RNA-related research.

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