Abstract:SUMMARYEffects of three representative vasodilators on peripheral and cardiac hemodynamics were studied in 20 patients with heart failure due to acute myocardial infarction (PCWP>18mmHg, Cl>2.20 L/min/m2) using venous occlusion plethysmography and a SwanGanz catheter. Sublingual isosorbide dinitrate (ISDN) significantly increased calf venous capacitance (CVC) from 5 to 60min (p<0.01) and calf blood flow (CBF) in the initial 15min (p<0.05), while simultaneously lowering PCWP (p<0.05) and central venous pressure… Show more
“…Vasodilator therapy is now commonly used in the management of heart failure complicating AMI and this supports the present findings regarding the peripheral vascular pathophysiology of AMI. 33) …”
“…Vasodilator therapy is now commonly used in the management of heart failure complicating AMI and this supports the present findings regarding the peripheral vascular pathophysiology of AMI. 33) …”
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