Unleashing the power of shark variable single domains (VNARs): broadly neutralizing tools for combating SARS-CoV-2
Olivia Cabanillas-Bernal,
Blanca J. Valdovinos-Navarro,
Karla E. Cervantes-Luevano
et al.
Abstract:The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a joint global effort to develop vaccines and other treatments that could mitigate the negative effects and the rapid spread of the virus. Single-domain antibodies derived from various sources, including cartilaginous fish, camelids, and humans, have gained attention as promising therapeutic tools against coronavirus disease 2019. Shark-derived variable new antigen receptors (VNARs) have emerged as the smallest na… Show more
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