Universal newborn hearing screening using A-TEOAE and A-ABR: The experience of a large public hospital

Cianfrone, Francesca; Mammarella, Fulvio; Ralli, Massimo; Evetovic, V; Pianura, Claudio Maria; Bellocchi, Gianluca

doi:10.3233/npm-181744

Cited by 14 publications

(11 citation statements)

References 32 publications

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“…Stage one screening is performed on infants aged 2-3 days, using TEOAEs by providing a stimulus in the form of sequential clicking sounds with a frequency range of 1,5-4,5 kiloHertz (kHz) and a wave intensity of 70 decibels (dB) Sound Pressure Level (SPL). 6,9,10,11 Results are divided into three categories, namely infants without hearing risk factors with bilateral pass responses considered to have normal hearing and excluded from further analysis, information about progressive genetic hearing loss remains given to families. Infants without risk factors with one or both sides refer responses are advised to take the TEOAEs test again one week after discharge.…”

Section: Stage Onementioning

confidence: 99%

“…The examination is based on sound intensity with click stimulation at 40 dB NHL. 9,10 The examination results are divided into, infants with normal AABR or 40dB hearing intensity with no risk factors for hearing loss. Infants with normal AABR or 40dB hearing intensity with a history of high risk or hereditary hearing loss in the family are advised to test hearing function with TEOAEs, ABR, tympanometry and acoustic signal reflexes routinely every six months in the first three years, then every 12 months in three the following year, infants with abnormal results in one ear or both ears are recommended for a diagnostic ABR examination.…”

Section: Stage Twomentioning

confidence: 99%

“…Subsequent interwave latency describes the function of the vestibulocochlear nerve and brain stem that is relatively unaffected by conductive or sensory hearing loss. 9 Auditory Brainstem Response has two main uses in hearing screening. First, as an audiometric test, it provides information about the ability of the peripheral auditory system to transmit information to the auditory nerve and so on.…”

Section: Indications For Auditory Brainstem Response Checksmentioning

confidence: 99%

“…Some countries divide into three levels of screening, where there are similarities in first and second level screening, but in the third level diagnostic BERA is added. 4,7,9,10 The Screen-Rescreen-Confirmation method should be recommended in Universal Newborn Hearing Screening (UNHS) gradually using OAE and ABR. Screening is done within the first four weeks, then repeated together with the immunization schedule in six months and starting an appropriate intervention at the age of the six-month-old child.…”

mentioning

confidence: 99%

“…4 Retrospective studies of the UNHS program in Italian public hospitals report that hearing evaluation with a combination of OAEs,and AABR can reduce errors in undiagnosed SNHL. 9…”

mentioning

confidence: 99%

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Newborns Hearing Screening With Otoacoustic Emissions and Auditory Brainstem Response

Hamam

Purnami

2020

JCMPHR

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Hearing loss in newborns is a serious matter, if it is not quickly diagnosed and starts early intervention, a child will experience social, speech, language, cognitive, and academic impairments. There is a method of hearing screening in newborns, which is divided into two types, universal newborn hearing screening, and targeted newborn screening. Both of these methods use OAEs and ABR as objective examination tools. The hearing screening method varies in each country, this difference is based on the test equipment used, age, frequency, professionals involved in screening, referral procedures, funding, and coverage areas. Indonesia uses two stages of screening, while Italy, America, Nigeria, France, India, and Poland use two to five stages of screening. Hearing screening of newborns using OAEs and ABR has a sensitivity of 100% and specificity of 99,3%.

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Section: Stage Onementioning

confidence: 99%

Section: Stage Twomentioning

confidence: 99%

Section: Indications For Auditory Brainstem Response Checksmentioning

confidence: 99%

mentioning

confidence: 99%

“…4 Retrospective studies of the UNHS program in Italian public hospitals report that hearing evaluation with a combination of OAEs,and AABR can reduce errors in undiagnosed SNHL. 9…”

mentioning

confidence: 99%

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Newborns Hearing Screening With Otoacoustic Emissions and Auditory Brainstem Response

Hamam

Purnami

2020

JCMPHR

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Ototoxic and nephrotoxic drugs in neonatal intensive care units: results of a Spanish and Italian survey

Arribas,

Decembrino,

Raffaeli

et al. 2024

Eur J Pediatr

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Background. Neonates face heightened susceptibility to drug toxicity, often exposed to off-label medications with dosages extrapolated from adult or pediatric studies. Premature infants in Neonatal Intensive Care Units (NICUs) are particularly at risk due to underdeveloped pharmacokinetics and exposure to multiple drugs. The study aimed to survey commonly used medications with a higher risk of ototoxicity and nephrotoxicity in Spanish and Italian NICUs.Methods. A prospective cross-sectional study was conducted in Italian and Spanish NICUs using a webbased survey with 43 questions. A modi ed Delphi method involved experts re ning the survey through online consensus. Ethical approval was obtained, and responses were collected from January to July 2023. The survey covered various aspects, including drug-related ototoxic and nephrotoxic management, hearing screening, and therapeutic drug monitoring.Results. Responses from 131 participants (35.9% from Spain and 64.1% from Italy) revealed awareness of drug toxicity risks. Varied practices were observed in hearing screening protocols, and a high prevalence of ototoxic and nephrotoxic drug use, including aminoglycosides (100%), vancomycin (70.2%), loop diuretics (63.4%), and ibuprofen (62.6%). Discrepancies existed in guideline availability and adherence, with differences between Italy and Spain in therapeutic drug monitoring practices.Conclusions. The study underscores the need for clinical guidelines and uniform practices in managing ototoxic and nephrotoxic drugs in NICUs. Awareness is high, but inconsistencies in practices indicate a necessity for standardization, including the implementation of therapeutic drug monitoring and the involvement of clinical pharmacologists. Addressing these issues is crucial for optimizing neonatal care in Southern Europe.The Joint Committee on Infant Hearing (JCIH) identi es ototoxic drugs like aminoglycosides and loop diuretics as risk indicators for hearing loss, so hearing screening is recommended [18; 19]. Recently, vancomycin was linked to hearing loss in very low birth weight infants [20].Apart from previously mentioned drugs, potential ototoxic and nephrotoxic agents encompass antibiotics (e.g., piperacillin/tazobactam), nonsteroidal anti-in ammatory drugs (indomethacin, ibuprofen), antivirals (acyclovir), antifungals (amphotericin B), angiotensin-converting enzyme inhibitors (captopril, enalapril), and spironolactone [21][22][23][24][25][26][27][28][29][30].Newborns on these drugs require close kidney function monitoring for acute kidney injury (AKI) and chronic kidney disease (CKD). A single-center study revealed that 70% of children had lasting kidney damage after nephrotoxic medication-induced AKI [31]. However, diagnosing drug-induced AKI (D-AKI) is complex due to varying criteria, hindering accurate identi cation [32][33][34].Considering that the above-mentioned drugs are among the most commonly used in neonatology, we conducted a survey in Spanish and Italian neonatal units on the use and management of drugs with a higher...

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Auditory brainstem response in preterm infants with bilirubin encephalopathy

Okumura

Kitai

Arai

et al. 2021

Early Human Development

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Universal newborn hearing screening using A-TEOAE and A-ABR: The experience of a large public hospital

Abstract: A correct and early diagnosis of hearing loss is mandatory to prevent permanent consequences; the spread of hearing screening programs is the optimal solution to reach this goal.

Cited by 14 publications

References 32 publications

Newborns Hearing Screening With Otoacoustic Emissions and Auditory Brainstem Response

Newborns Hearing Screening With Otoacoustic Emissions and Auditory Brainstem Response

Ototoxic and nephrotoxic drugs in neonatal intensive care units: results of a Spanish and Italian survey

Auditory brainstem response in preterm infants with bilirubin encephalopathy

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