Universal Healthcare for Zebrafish

Varga, Zoltán; Lawrence, Christian; Ekker, Stephen C.; Eisen, Judith S

doi:10.1089/zeb.2016.1311

Cited by 2 publications

(1 citation statement)

References 31 publications

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“… Santoriello and Zon, 2012 ; García-Caballero et al, 2018 ; Varga et al, 2018 ; Truong and Artinger, 2021 ) and its husbandry conditions standardized to respect their natural conditions ( Engeszer et al, 2007 ; Arunachalam et al, 2013 ). Although not present in many international directives, a consensus on animal care has almost been reached ( Geisler et al, 2016 ; Lawrence, 2016 ; Varga et al, 2016 ; Lidster et al, 2017 ; Aleström et al, 2020 ), which is becoming crucial for its worldwide pre-clinical use.…”

Section: Zebrafish Models For Human Skeletal Diseasesmentioning

confidence: 99%

Zebrafish Models for Human Skeletal Disorders

2021

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In 2019, the Nosology Committee of the International Skeletal Dysplasia Society provided an updated version of the Nosology and Classification of Genetic Skeletal Disorders. This is a reference list of recognized diseases in humans and their causal genes published to help clinician diagnosis and scientific research advances. Complementary to mammalian models, zebrafish has emerged as an interesting species to evaluate chemical treatments against these human skeletal disorders. Due to its versatility and the low cost of experiments, more than 80 models are currently available. In this article, we review the state-of-art of this “aquarium to bedside” approach describing the models according to the list provided by the Nosology Committee. With this, we intend to stimulate research in the appropriate direction to efficiently meet the actual needs of clinicians under the scope of the Nosology Committee.

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