Univariable and multivariable mendelian randomization study revealed the modifiable risk factors of urolithiasis
Hailin Fang,
Jiwang Deng,
Qingjiang Chen
et al.
Abstract:Background
Urolithiasis is a common urological disease with increasing incidence worldwide, and preventing its risk poses significant challenges. Here, we used Mendelian randomization (MR) framework to genetically assess the causal nature of multifaceted risk factors on urolithiasis.
Methods
17 potential risk factors associated with urolithiasis were collected from recently published observational studies, which can be categorized basically into lifestyle factors and circulating biomarkers. The instrumental … Show more
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