Uniqueness of laryngeal nerve injury following heart transplantation

Rosa, Angelo de la; Aguilar, José Luis Fernández; Barbu, Anca M.; Chang, D.; Kobashigawa, J.A.

doi:10.1111/ctr.14075

Cited by 3 publications

(4 citation statements)

References 28 publications

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“…12,19,34 Angelo et al found that the incidence of newly established recurrent laryngeal nerve injuries in HTPL patients was 2.9%, which was higher than that in general cardiothoracic surgery but lower than that in aortic arch surgery. [35][36][37] Our data show that the incidence of vocal cord abnormalities was higher than in previous reports. It could be because we enrolled all patients with impaired vocal fold motion (vocal cord paresis), and some of them showed improvement over time.…”

Section: Discussioncontrasting

confidence: 65%

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Prevalence and clinical predictors of dysphagia after heart transplantation

Hong

Kang

et al. 2023

Clinical Transplantation

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Introduction: Dysphagia is a common complication after heart transplantation (HTPL), but few studies exist on dysphagia after HTPL, and the prevalence is unknown. The objective of our current study was to establish the prevalence and risk factors for dysphagia after HTPL and to classify its characteristics through Videofluoroscopic Swallowing Studies (VFSS). Methods:The recipients of HTPL carried out at a single center from January 2011 to November 2019 were assessed retrospectively. Dysphagia was evaluated by a bedside swallowing exam and VFSS to evaluate for evidence of aspiration. The duration of ventilator and preoperative extracorporeal membrane oxygenation (ECMO) support, intensive care unit, hospital stay, the progress of oral feeding after surgery, the presence of a tracheostomy, and vocal cord palsy were analyzed. On the third and seventh days following surgery, we looked at the relationship between risk factors and oral feeding progress, respectively. Additionally, we contrasted these risk variables with the no penetration/aspiration (PA) group and the PA group on VFSS.Results: Among the study cohort of 421 patients, 222 (52.7%) patients had access to oral feeding on the third day of surgery. The number of patients who underwent VFSS due to clinically suspected dysphagia was 96 (22.8%). Of these, 54 (56.2%) had aspiration or penetration (PA group), while 42 (43.8%) had no abnormal findings (No-PA group). In the multivariable regression model, preoperative ECMO support, vocal cord abnormalities, tracheostomy, and emergent need for HTPL were identified as independent risk variables for oral feeding progress on postoperative days (PODs) 3 and 7. Among these factors, preoperative ECMO support had the highest odds ratio (OR)

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Section: Discussioncontrasting

confidence: 65%

“…Angelo et al. found that the incidence of newly established recurrent laryngeal nerve injuries in HTPL patients was 2.9%, which was higher than that in general cardiothoracic surgery but lower than that in aortic arch surgery 35–37 . Our data show that the incidence of vocal cord abnormalities was higher than in previous reports.…”

Section: Discussioncontrasting

confidence: 55%

Prevalence and clinical predictors of dysphagia after heart transplantation

Hong

Kang

et al. 2023

Clinical Transplantation

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“…According to the International Society for Heart and Lung Transplantation registry, the number of global heart transplants is nearing 6000 every year. 33 Compared to the number of HF patients, heart transplantation is difficult to popularize obviously. Other complications such as allograft rejection also limits its application.…”

Section: Heart Transplantationmentioning

confidence: 99%

“…Heart transplantation is a more viable option for appropriate patients with end‐stage cardiac disease with the improvement of immunosuppression and surgical techniques. According to the International Society for Heart and Lung Transplantation registry, the number of global heart transplants is nearing 6000 every year 33 . Compared to the number of HF patients, heart transplantation is difficult to popularize obviously.…”

Section: Hf Classification and Conventional Treatmentsmentioning

confidence: 99%

Recent advances in implantable hydrogels for treating heart failure

Wan

Sun

Zhang

et al. 2022

J of Applied Polymer Sci

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Heart failure (HF) is an irreversible disease characterized by the reducing capacity of blood supply as a consequence of cardiomyocyte death and deteriorated fibrosis. There is a lack of effective treatment for heart failure other than a heart transplant, and thus significant resources have been dedicated to developing functional materials for cardiac tissue engineering. Implanting hydrogels in the myocardium near the myocardial infarction area can preserve cardiac function and slow the remodeling that leads to HF by providing mechanical support to the ventricular wall. Nevertheless, few reviews have been published for this promising HF treatment. Herein, we briefly discuss the classification and existing conventional treatments for HF and provide an overview of recent functional hydrogels designed for cardiac repair after myocardial infarction, including polymeric hydrogels, polymer‐cell complex hydrogels, polymer‐cytokine complex hydrogels, and polymer‐protein complex hydrogels. Key challenges and future directions for advanced hydrogels have also been discussed.

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