Unique territorial and compartmental organization of chromosomes in the holocentric silkmoth
J. Gil,
E. Navarrete,
L.F. Rosin
et al.
Abstract:The hallmarks of chromosome organization in multicellular eukaryotes are chromosome territories (CT), chromatin compartments, and different types of domains, including topologically associated domains (TADs). Yet, most of these concepts derive from analyses of organisms with monocentric chromosomes. Here we describe the 3D genome architecture of an organism with holocentric chromosomes, the silkwormBombyx mori. At the genome-wide scale,B. morichromosomes form highly separated territories and lack substantial t… Show more
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