Unique polyacetylenic ester-neolignan derivatives from Mitrephora tomentosa and their antimalarial activities

Triterpenes and Phenolic Compounds from Euphorbia deightonii with Antiviral Activity against Herpes Simplex Virus Type-2

“…However, unlike in dihydrocarinatinol, the allyl side chain of 4 is substituted with a methoxy group, as shown by the HMBC correlations of C-7’ ( δ C 84.8) with H-9’ ( δ H 5.23 and 5.29) and 7′-OCH 3 ( δ H 3.34), while the hydroxymethyl moiety is acetylated, as suggested by heteronuclear correlations between the acetyl carbonyl ( δ C 170.9) and H 2 -9 oxymethylene protons ( δ H 4.29 and 4.47). The vicinal coupling constant value of 7.6 Hz between H-7 and H-8 dictated their trans relationship [ 11 ]. Trivial name deightonin was given for 4 ; its chemical name is trans -(2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-5-(1-methoxyallyl)-2,3-dihydrobenzofuran-3-yl)methyl acetate.…”

Isolation and structure elucidation of biological active compounds from Euphorbia deightonii and Centrapalus pauciflorus

“…124 Based on their NMR data, ED-1 (28) and ED-134 (29) were proven to be ent-atisane diterpenoids known metabolites of Euphorbiaceae species. ED-1 (28) was isolated from E. pilosa, 125 137 Trivial name deightonin was given to ED-119 (34); its chemical name is trans- and 7). From these data it could be concluded that VP-146 (39) and VP-147 (40) are stereoisomers.…”