Unique miRNA Expression Profile in MSI- and EMAST-Unstable Sporadic Colon Cancer
Sonja Marinović,
Kristina Vuković Đerfi,
Anita Škrtić
et al.
Abstract:MicroRNAs (miRNAs) are critical post-transcriptional gene regulators and their involvement in sporadic colon cancer (CRC) tumorigenesis has been confirmed. In this study we investigated differences in miRNA expression in microsatellite stable (MSS/EMAST-S), microsatellite unstable marked by high elevated microsatellite alterations at selected tetranucleotide repeats (MSS/EMAST-H), and high microsatellite unstable (MSI-H/EMAST-H) tumor subgroups as well as in tumors with different clinicopathologic characterist… Show more
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