Unique case of growth hormone (GH) deficiency accompanied by clinical anophthalmia, hypoplastic orbits, digital dysplasia, short stature, obesity, and diabetes mellitus

An unusual ocular manifestation in Fanconi anemia: Congenital glaucoma

“…Although we cannot entirely exclude the possibility of a coincidental occurrence, it may be reasonable to assume that severe growth hormone deficiency in the proband might be involved in development of CG. In medical literature are a remarkable number of reports stating that growth hormone is needed for normal eye development and that, in cases of growth hormone deficiency, a variety of dysgenesis in the eyes may develop [4][5][6][7]. An FA patient with growth hormone deficiency in whom various ocular developmental abnormalities are displayed has been reported as well [8].…”