Union rates and prognostic variables of osteoporotic vertebral fractures treated with a rigid external support

Murata, Kenji; Watanabe, Goichi; Kawaguchi, Satoshi; Kanaya, Kohei; Horigome, Keiko; Yajima, Hideki; Morita, Tomonori; Yamashita, Toshihiko

doi:10.3171/2012.7.spine122

Cited by 34 publications

(52 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Eventually, 10 articles were included in this study (10111213141516171819) and 4 RCTs, with 281 participants, were included in meta-analysis (10111214) (Fig. 1).…”

Section: Resultsmentioning

confidence: 99%

“…As summarized in Table 1 and 2, 6 RCTs (101112131415), 1 non-randomized controlled trial (19) and 3 observational studies (161718) were included. Characteristics of studies varied a lot but all had limited number of participants and only one trial had a sample size merely above 100 (12).…”

Section: Resultsmentioning

confidence: 99%

“…Phase of fracture and recruiting sources of participants were different between studies. Participants had acute fractures in 3 trials (101418) while those from another 3 trials had sub-acute fractures (111213). Most of the studies recruited participants in hospital environment (10131415171819), while two trials recruited in community environment (1112).…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Effect of Brace to Osteoporotic Vertebral Fracture: a Meta-Analysis

Jin

Lee

2016

J Korean Med Sci

View full text Add to dashboard Cite

Brace is one of the most commonly used interventions to manage osteoporotic vertebral fracture. However, its authentic effectiveness remains unclear. The aim of this study was to investigate the efficacy of brace in patients with osteoporotic vertebral fractures. We conducted a literature review and meta-analysis following the guideline and handbook of the Cochrane collaboration. Ten published articles were included in this study and data from 4 randomized controlled trials were analyzed. Low quality evidence proved using Spinomed brace could bring large and significant beneficial effect to patients with sub-acute osteoporotic vertebral fractures. Very low quality evidence proved no significant difference between Spinomed orthosis, rigid brace and soft brace when they were used in patients with acute fractures. Therefore, it might be applicable to recommend middle term use of Spinomed orthosis to patients with subacute fracture. In addition, this study emphasized the need for high quality randomized controlled trials.

show abstract

“…Eventually, 10 articles were included in this study (10111213141516171819) and 4 RCTs, with 281 participants, were included in meta-analysis (10111214) (Fig. 1).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Brace to Osteoporotic Vertebral Fracture: a Meta-Analysis

Jin

Lee

2016

J Korean Med Sci

View full text Add to dashboard Cite

show abstract

“…14,32 In the lumbar spine, a single report has identified age < 80 years as a predictor of the level of functioning following thoracolumbar spine fracture. 44 Bone healing following thoracolumbar compression and/ or burst fracture appears to be reduced in the elderly 33 but has yet to be systematically studied. 19 However, the consequences of such findings remain unclear, and the risk profile associated with managing lumbar spine trauma in the elderly has yet to be systematically studied.…”

mentioning

confidence: 99%

Perioperative morbidity and mortality after lumbar trauma in the elderly

Winkler¹,

Yue²,

Birk³

et al. 2015

FOC

View full text Add to dashboard Cite

OBJECT Traumatic fractures of the thoracolumbar spine are common injuries, accounting for approximately 90% of all spinal trauma. Lumbar spine trauma in the elderly is a growing public health problem with relatively little evidence to guide clinical management. The authors sought to characterize the complications, morbidity, and mortality associated with surgical and nonsurgical management in elderly patients with traumatic fractures of the lumbar spine. METHODS Using the National Sample Program of the National Trauma Data Bank, the authors performed a retrospective analysis of patients ≥ 55 years of age who had traumatic fracture to the lumbar spine. This group was divided into middle-aged (55–69 years) and elderly (≥ 70 years) cohorts. Cohorts were subdivided into nonoperative, vertebroplasty or kyphoplasty, noninstrumented surgery, and instrumented surgery. Univariate and multivariable analyses were used to characterize and identify predictors of medical and surgical complications, mortality, hospital length of stay, ICU length of stay, number of days on ventilator, and hospital discharge in each subgroup. Adjusted odds ratios, mean differences, and associated 95% CIs were reported. Statistical significance was assessed at p < 0.05, and the Bonferroni correction for multiple comparisons was applied for each outcome analysis. RESULTS Between 2003 and 2012, 22,835 people met the inclusion criteria, which represents 94,103 incidents nationally. Analyses revealed a similar medical and surgical complication profile between age groups. The most prevalent medical complications were pneumonia (7.0%), acute respiratory distress syndrome (3.6%), and deep venous thrombosis (3%). Surgical site infections occurred in 6.3% of cases. Instrumented surgery was associated with the highest odds of each complication (p < 0.001). The inpatient mortality rate was 6.8% for all subjects. Multivariable analyses demonstrated that age ≥ 70 years was an independent predictor of mortality (OR 3.16, 95% CI 2.77–3.60), whereas instrumented surgery (multivariable OR 0.38, 95% CI 0.28–0.52) and vertebroplasty or kyphoplasty (OR 0.27, 95% CI 0.17–0.45) were associated with decreased odds of death. In surviving patients, both older age (OR 0.32, 95% CI 0.30–0.34) and instrumented fusion (OR 0.37, 95% CI 0.33–0.41) were associated with decreased odds of discharge to home. CONCLUSIONS The present study confirms that lumbar surgery in the elderly is associated with increased morbidity. In particular, instrumented fusion is associated with periprocedural complications, prolonged hospitalization, and a decreased likelihood of being discharged home. However, fusion surgery is also associated with reduced mortality. Age alone should not be an exclusionary factor in identifying surgical candidates for instrumented lumbar spinal fusion. Future studies are needed to confirm these findings.

show abstract

“…Until now it is not known as to whether the extensive filling of cement in a vertebral body has an adverse effect on bony healing [24]. …”

Section: Introductionmentioning

confidence: 99%

Cementless Fixation of Osteoporotic VCFs Using Titanium Mesh Implants (OsseoFix): Preliminary Results

Eschler

Ender

Ulmar

et al. 2014

BioMed Research International

View full text Add to dashboard Cite

Introduction. Vertebral compression fractures (VCFs) affect 20% of people over the age of 70 with increasing incidence. Kypho-/vertebroplasty as standard operative procedures are associated with limitations like cement leakage, limited reduction capabilities, and risk for adjacent fractures. To address these shortcomings, we introduce a new minimal invasive cementless VCF fixation technique. Methods. Four patients (72.3 years, range 70–76) with VCFs type AO/Müller A1.3 and concomitant osteoporosis were treated by minimal invasive transpedicular placement of two intervertebral mesh cages for fracture reduction and maintenance. Follow-up included functional/radiological assessment and clinical scores and averaged 27.7 months (24–28). Results. Endplate reduction was achieved in all cases (mean surgery time: 28.5 minutes). Kyphotic (KA) and Cobb angle revealed considerable improvements postoperatively (KA 14.5° to 10.7°/Cobb 10.1° to 8.3°). Slight loss of vertebral reduction (KA: 12.6°) and segment rekyphosis (Cobb: 10.7°) were observed for final follow-up. Pain improved from 8.8 to 2.8 (visual analogue scale). All cases showed signs of bony healing. No perioperative complications and no adjacent fractures occurred. Conclusion. Preliminary results in a small, selected patient collective indicate the ability of bony healing for osteoporotic VCFs. Cementless fixation using intravertebral titanium mesh cages revealed substantial pain relief, adequate reduction, and reduction maintenance without complications. Trial registration number is DRKS00005657, German Clinical Trials Register (DKRS).

show abstract

Union rates and prognostic variables of osteoporotic vertebral fractures treated with a rigid external support

Cited by 34 publications

References 37 publications

Effect of Brace to Osteoporotic Vertebral Fracture: a Meta-Analysis

Effect of Brace to Osteoporotic Vertebral Fracture: a Meta-Analysis

Perioperative morbidity and mortality after lumbar trauma in the elderly

Cementless Fixation of Osteoporotic VCFs Using Titanium Mesh Implants (OsseoFix): Preliminary Results

Contact Info

Product

Resources

About