1999
DOI: 10.1159/000018232
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Unilesional Follicular Mycosis fungoides

Abstract: Follicular mycosis fungoides (FMF) is an unusual clinical and histological variant of MF, characterized by selective involvement of hair follicles by atypical lymphocytes. We describe a female patient who had follicular papules located only on the medial aspect of her right thigh. To the best of our knowledge, this patient represents the first reported case of unilesional FMF.

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Cited by 24 publications
(30 citation statements)
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“…Of note are the 3 previously reported cases of unilesional MF in the head area [4, 8, 9]. There is only one previous report of folliculotropic MF of a localized nature in the literature [12]; in this case, as in ours, there was no evidence of mucin deposit, and this is in keeping with multilesional MF, in which cases indistinguishable clinically from follicular mucinosis but without evidence of mucin deposit have been reported [20]. …”
Section: Discussionsupporting
confidence: 85%
See 1 more Smart Citation
“…Of note are the 3 previously reported cases of unilesional MF in the head area [4, 8, 9]. There is only one previous report of folliculotropic MF of a localized nature in the literature [12]; in this case, as in ours, there was no evidence of mucin deposit, and this is in keeping with multilesional MF, in which cases indistinguishable clinically from follicular mucinosis but without evidence of mucin deposit have been reported [20]. …”
Section: Discussionsupporting
confidence: 85%
“…The few reports appearing in the literature since 1981 [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13], usually using the term ‘unilesional MF’ [3, 4, 5, 6, 7, 8, 9, 12], indicate that this variant of MF is rare, presenting as an isolated patch or plaque, generally indistinguishable clinically and histopathologically from typical MF. It follows a benign course for long periods without any treatment, and the initial reports stressed that there had been no case of disease recurrence after curative-intent treatment after variable follow-up periods [1, 2, 3, 4, 5, 6, 7].…”
Section: Introductionmentioning
confidence: 99%
“…10 Since the first report in 1981, 8 approximately 128 cases of solitary MF have been described, usually termed 'unilesional MF'. 5,6,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Solitary MF can affect any age group and has been reported in children. 17,19 The mean age of our patients was 47 years, with one case occurring in a 14-year-old girl.…”
Section: Discussionmentioning
confidence: 99%
“…The most noteworthy clinical finding in our series is the association between ichthyosiform manifestations and skin lesions typical of so-called FMF, an unusual clinicopathologic variant of MF characterized by selective involvement of hair follicles by the atypical T lymphocytes [1, 2, 3, 4]. Such skin lesions, including comedo-like lesions and epidermal cysts, alopecia and follicular keratotic papules, were seen in 3 of 4 patients, whereas cutaneous manifestations of classic MF were absent in all 4 cases.…”
Section: Discussionmentioning
confidence: 99%
“…Cutaneous manifestations typically comprise patches, plaques and tumors. Atypical variants include, among others, follicular [1, 2, 3], unilesional [4], bullous [5], hypopigmented [6]and invisible [7]MF. To the best of our knowledge, only one case of MF presenting solely with the clinical features of acquired ichthyosis has been reported [8].…”
Section: Introductionmentioning
confidence: 99%