Unilateral recurrent macular hole in a patient with retinitis pigmentosa: a case report

Abstract

IntroductionSeveral macular complications related to abnormalities of the vitreoretinal interface have been classically attributed to retinitis pigmentosa of which cystoid macular edema is the most common. Other less frequent complications are as follows: epiretinal membranes, vitreomacular traction syndrome and macular holes.Case presentationA 64-year-old woman, with the previous diagnosis of retinitis pigmentosa, was referred to our department with a complaint of central visual loss in her left eye for 12 months. A fundoscopy and optical coherence tomography examination revealed the presence of a macular hole more than 500 microns in diameter. The patient underwent 20-gauge pars plana vitrectomy. Closure of the hole was observed after surgery, but reopening occurred at 2 years postoperatively.ConclusionThe pathogenesis of macular hole formation in patients with retinitis pigmentosa is unclear. Surgical outcomes may not always be favorable, and the possibility of reopening must be taken into account, even after a long time.

Management of Full-Thickness Macular Hole in A Genetically Confirmed Case with Usher Syndrome

“…Moreover, in three patients the FTMH failed to close after one vitrectomy and resulted in worse VA [10,14,18]. Of note, FTMH reopening after successful surgical intervention has been reported in one patient [17]. Based on these studies, a successful closure of the macular hole is achieved in the majority of the cases, whereas the visual outcomes seem to be mostly positive but can be variable.…”

“…The role of vitrectomy is established in the treatment of idiopathic FTMH leading to a high closure rate and significant VA improvement compared to observation [16]. However, due to the rarity of FTMH cases in the context of RP, surgical outcomes have only been reported in a few small case series including patients with heterogeneous characteristics such as RP stage, symptoms duration, baseline VA, FTMH size and ocular comorbidities [10,12,14,15,17,18]. Eight RP cases with FTMH have been reported to have a successful anatomic outcome with seven of them showing higher post-operative VA and one of them having unaltered VA [10,14,15,18].…”

Flap technique-assisted surgeries for advanced retinitis pigmentosa complicated with macular hole: a case report and literature review

“…PPV, ILM peeling, LHEP transplantation, autologous blood, C3F8 injection2. PPV, ILM peeling, laser, LHEP transplantation, C3F8 injection 2 improved 2 complete FTMH closure Yan et al [ 14 ] 2018 China 4 4 PPV, ILM peeling, SF6 or C3F8 or silicon injection 2 improved, 1 unchanged, 1 worsened 3 complete FTMH closure,1 remained unclosed Ratra et al [ 22 ] 2013 India 5 5 CME PPV, ILM peeling, C3F8 or silicon injection 2 improved, 1 unchanged, 2 worsened 3 complete FTMH closure,2 remained unclosed Enani et al [ 23 ] 2017 Saudi Arabia 1 1 PPV, ILM peeling, gas tamponade 1 unchanged 1 complete FTMH closure García-Fernández et al [ 24 ] 2013 Spain 1 1 SRF, PVD PPV, ILM peeling, SF6 injection 1 unchanged 1 reopened 2 years later Amemiya et al [ 25 ] 2002 Japan 1 1 PPV, ILM peeling, gas tamponade 1 improved 1 complete FTMH closure PPV pars plana vitrectomy; ILM internal limiting membrane; FTMH full-thickness macular hole; PVD posterior vitreous detachment; RD retinal detachment; CME cystoid macular edema; EZ ellipsoid zone; RPE retinal pigment epithelium; LHEP lamellar-...…”

Bilateral Lamellar Macular Hole Surgery in Retinitis Pigmentosa

“…3,4 There have been a few small case series reporting vision improvement after pars plana vitrectomy in patients with retinitis pigmentosa and macular holes. 2,5,6 To the authors' knowledge, there have been no cases reported in the literature on the repair of lamellar macular holes in patients with retinitis pigmentosa. Recent studies support favorable visual and anatomical outcomes in symptomatic patients undergoing pars plana vitrectomy for lamellar macular hole repair.…”