Unilateral negative electroretinogram presenting as photophobia

Kido, Ai; Ogino, Ken; Miyake, Yoichi; Yanagida, Kazuo; Kikuchi, Takanobu; Yoshimura, Nagahisa

doi:10.1007/s10633-016-9544-z

Cited by 5 publications

(8 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…AIR is characterized by an older age of onset. In unilateral cases, five males and three females, seven Japanese, and one Caucasian were reported by Hirakata et al [76], and two males and two females, four Japanese, were reported by Kido et al [77]. Patients' demographic of unilateral retinopathy is shown in Table 1.…”

Section: Patients' Demographicmentioning

confidence: 93%

“…AIR often affects the outer retinal layers; however, recently, a rare type of AIR has been reported, which damages the inner retinal layers is suspected. Moreover, Hirakata et al reported eight cases of unilateral retinopathy [76], Kido et al reported four cases [77], and Ueno et al reported three cases of bilateral retinopathy [78]. All these cases have been reported in Japan.…”

Section: Acute Inner Retinal Dysfunctionmentioning

confidence: 99%

“…Patients' demographic of unilateral retinopathy is shown in Table 1. Additionally, the mean age at the onset of symptoms was 62.2 ± 7.9 years (range 48-76), and three patients had a history of systemic autoimmune diseases, including asthma, palmoplantar pustulosis, and polymyalgia rheumatic [76,77].…”

Section: Patients' Demographicmentioning

confidence: 99%

“…The majority of the patients experienced sudden and severe photophobia in one eye [76,77], and some patients required dark glasses to walk under light-adapted conditions. Additionally, some patients developed visual field loss in the affected eye, which was especially severe under light-adapted conditions.…”

Section: Symptomsmentioning

confidence: 99%

“…Although patients suffered from photophobia, visual acuity was relatively well preserved in most patients [76,77]. Additionally, visual field patterns of Goldmann perimetry (GP) varied in the affected eyes, from almost normal to narrow isopters and scotomas compared with the fellow eye.…”

Section: Visual Acuity and Visual Fieldmentioning

confidence: 99%

See 4 more Smart Citations

Retinal Dysfunction Caused by Autoimmune Mechanisms

Hirakata¹

2023

Medical and Surgical Retina - Recent Innovation, New Perspective, and Applications

View full text Add to dashboard Cite

Autoimmune retinal disorders have been identified, including acute zonal occult outer retinopathy (AZOOR), AZOOR complex, autoimmune retinopathy (AIR) comprising paraneoplastic AIR (pAIR), cancer-associated retinopathy (CAR), melanoma-associated retinopathy (MAR), and non-paraneoplastic AIR (npAIR). Patients with autoimmune retinal disorders typically present with sudden or acute onset of photopsia, photophobia, night blindness, rapid visual loss, and visual field abnormalities. The combination of multimodal imaging and electrophysiology is crucial because these diseases are challenging to diagnose. In particular, electroretinograms (ERGs) are essential for diagnosis. However, no treatment has been established to date. Additionally, a case of inner retinal dysfunction, thought to be a type of AIR, was recently reported. The diagnosis is difficult because most cases occur in one eye, and although the patient complains of severe photophobia, retinal imaging is almost normal, vision is preserved and there is almost no progression. The ERG is very characteristic, with cone-rod dysfunction and negative ERG. This chapter describes in detail the characteristics of AZOOR, AIR, and acute inner retinal dysfunction as new phenotypes of AIR.

show abstract

Section: Patients' Demographicmentioning

confidence: 93%