Unilateral axillary adenopathy in the setting of COVID-19 vaccine: Follow-up

Mehta, Neelesh B.; Sales, Rachel Marcus; Babagbemi, Kemi; Levy, Allison; McGrath, Anika L.; Drotman, Michele; Dodelzon, Katerina

doi:10.1016/j.clinimag.2021.06.037

Cited by 8 publications

(6 citation statements)

References 4 publications

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“…In patients with newly diagnosed breast cancer, clearly, breast and axillary should be performed without any delays. The follow-up time of at least 12 weeks post-COVID-19 vaccination is in line with the studies of Mehta et al and Nguyen et al demonstrating normalization of axillary lymph nodes at US 12–16 weeks post-COVID-19 vaccination in most of the patients [20] , [21] . There are currently no reports of persistant vaccine induced lymphadenopathy on US after a follow-up period more than 16 weeks.…”

Section: Methodssupporting

confidence: 89%

Axillary lymph node characteristics in breast cancer patients versus post-COVID-19 vaccination: Overview of current evidence per imaging modality

Nijnatten

Jochelson

Lobbes

2022

European Journal of Radiology

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Section: Methodssupporting

confidence: 89%

Axillary lymph node characteristics in breast cancer patients versus post-COVID-19 vaccination: Overview of current evidence per imaging modality

Nijnatten

Jochelson

Lobbes

2022

European Journal of Radiology

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“…Several recent publications have described a combination of lymphadenopathy and abnormal PET findings in patients vaccinated against COVID-19. However, these primarily detailed cases involve the BNT162b2 and messenger RNA (mRNA)-1273 vaccines 5 6…”

Section: Discussionmentioning

confidence: 99%

Prolonged febrile illness following first dose of ChAdOx1

Caruana Dingli,

Bugeja,

Camilleri

2023

BMJ Case Rep

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A woman in her 40s, with a known history of fibromyalgia, presented with high-grade fever and constitutional symptoms occurring 5 days following vaccination with Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1). Her inflammatory markers and neutrophil count were found to be elevated and as such, she was started on antibiotics. Despite treatment, markers remained elevated and temperature spikes persisted for another 4 weeks before these symptoms subsided, and her blood tests normalised. All investigations taken in the interim were negative, with no source being identified for the fever. As a result, a positron emission tomography scan was performed to attempt to localise the source of these symptoms. This revealed low-to-moderate grade lymph node tracer uptake above and below the diaphragm most pervasive in the right axilla, with uptake in the right arm corresponding with the site of vaccination.

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“…More than half of the patients who experienced lymphadenopathy following the second immunisation had their cortical levels return to normal within a month. More research is needed to establish how long it takes to reach baseline values in the cortex [10]. Our work has a number of drawbacks, including a limited sample size, a focus on a single mRNA vaccination, and no US assessment of additional nodal sites (i.e., subclavian, submandibular).…”

Section: Discussionmentioning

confidence: 99%

Unilateral axillary lymphadenopathy following COVID-19 vaccination

Publishing

Patil

Kumar

2022

ijhs

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Objectives: COVID-19 vaccine effects on the lymph nodes of the axillary lymph nodes were examined in this study by comparing the characteristics of the nodes before and after immunisation. Methods: More than twenty-five employees who took part in the company's immunisation campaign were considered for employment. Before vaccination, one week after the first dose, and one week after the second dose, the ipsilateral vaccinated arm was examined by axillary ultrasonography. The total number of visible nodes, the maximum diameter and cortical measures, and Bedi's categorization were recorded. The Mann–Whitney U test was used to compare the collected data and determine the differences between the two groups. As long as the statistical significance threshold was met, the variables were regarded to be of interest to researchers. Results: There was a statistically significant increase in the number of visible nodes, maximal diameter, cortical thickness, and Bedi's classification grade (p 0.001) between the three US examinations. In comparison to patients who had previously been infected with COVID-19, those who were nave to the virus had a greater lymph node response.

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Unilateral axillary adenopathy in the setting of COVID-19 vaccine: Follow-up

Cited by 8 publications

References 4 publications

Axillary lymph node characteristics in breast cancer patients versus post-COVID-19 vaccination: Overview of current evidence per imaging modality

Axillary lymph node characteristics in breast cancer patients versus post-COVID-19 vaccination: Overview of current evidence per imaging modality

Prolonged febrile illness following first dose of ChAdOx1

Unilateral axillary lymphadenopathy following COVID-19 vaccination

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